幼儿自闭症改良检查表：一项调查自闭症谱系障碍早期检测的随访研究。
The modified checklist for autism in toddlers: a follow-up study investigating the early detection of autism spectrum disorders.
作者信息
Kleinman Jamie M, Robins Diana L, Ventola Pamela E, Pandey Juhi, Boorstein Hilary C, Esser Emma L, Wilson Leandra B, Rosenthal Michael A, Sutera Saasha, Verbalis Alyssa D, Barton Marianne, Hodgson Sarah, Green James, Dumont-Mathieu Thyde, Volkmar Fred, Chawarska Katarzyna, Klin Ami, Fein Deborah
机构信息
Department of Psychology, University of Connecticut, 406 Babbidge Rd., Storrs, CT 06269-1020, USA.
出版信息
J Autism Dev Disord. 2008 May;38(5):827-39. doi: 10.1007/s10803-007-0450-9.
Autism spectrum disorders (ASD) often go undetected in toddlers. The Modified Checklist for Autism in Toddlers (M-CHAT) was used to screen 3,793 children aged 16-30 months from low- and high-risk sources; screen positive cases were diagnostically evaluated. Rescreening was performed on 1,416 children aged 42-54 months. Time 1 Positive Predictive Value (PPV) was .36 for the initial screening and .74 for the screening plus follow-up telephone interview; values were similar for Time2 PPV. When separating referral sources, PPV was low for the low-risk sample but acceptable with the followup telephone interview. Children with ASD from the low-risk and high-risk samples were highly similar. Results indicate that the M-CHAT continues to be a promising instrument for the early detection of ASD.
自闭症谱系障碍（ASD）在幼儿中常常未被发现。使用改良幼儿自闭症检查表（M-CHAT）对来自低风险和高风险群体的3793名16至30个月大的儿童进行筛查；对筛查呈阳性的病例进行诊断评估。对1416名42至54个月大的儿童进行了再次筛查。第一次筛查时的阳性预测值（PPV）为0.36，筛查加后续电话访谈时为0.74；第二次PPV值相似。当区分转诊来源时，低风险样本的PPV较低，但后续电话访谈时可接受。来自低风险和高风险样本的ASD儿童高度相似。结果表明，M-CHAT仍然是早期检测ASD的一种很有前景的工具。
Zotero 插件