van Bentum P J M, Janssen J W G, Kentgens A P M, Bart J, Gardeniers J G E
Institute for Molecules and Materials, Radboud University, Toernooiveld 1, 6525ED Nijmegen, The Netherlands.
J Magn Reson. 2007 Nov;189(1):104-13. doi: 10.1016/j.jmr.2007.08.019. Epub 2007 Sep 7.
A novel route towards chip integrated NMR analysis is evaluated. The basic element in the design is a stripline RF 'coil' which can be defined in a single layer lithographic process and which is fully scalable to smaller dimensions. The sensitivity of such a planar structure can be superior to that of a conventional 3D helix. The basic properties, such as RF field strength, homogeneity and susceptibility broadening are discussed in detail. Secondary effects related to the thermal characteristics are discussed in simplified models. Preliminary NMR tests of basic solid and liquid samples measured at 600 MHz confirm the central findings of the design study. It is concluded that the stripline structure can be a valuable addition to the NMR toolbox; it combines high sensitivity with low susceptibility broadening and high power handling capabilities in a simple scalable design.
评估了一种通往芯片集成核磁共振分析的新途径。该设计中的基本元件是一种带状线射频“线圈”，它可以在单层光刻工艺中定义，并且可以完全缩放到更小的尺寸。这种平面结构的灵敏度可能优于传统的三维螺旋结构。详细讨论了诸如射频场强、均匀性和磁化率展宽等基本特性。在简化模型中讨论了与热特性相关的次要效应。在600兆赫下对基本固体和液体样品进行的初步核磁共振测试证实了设计研究的主要发现。得出的结论是，带状线结构可以成为核磁共振工具箱中有价值的补充；它在简单的可扩展设计中结合了高灵敏度、低磁化率展宽和高功率处理能力。
