Hong Ran, Lim Sung-Chul, Jung Hyuk
Department of Pathology, College of Medicine, Chosun University Hospital, Dong-Gu, Gwangju, South Korea.
Arch Gynecol Obstet. 2008 May;277(5):445-8. doi: 10.1007/s00404-007-0486-2. Epub 2007 Oct 20.
A liposarcoma is the most frequent soft tissue sarcoma found in adults, however, a liposarcoma arising in uterus is extremely rare. Indeed, a liposarcoma coexistent with a leiomyoma is even rarer and there is only one case has been reported in the English literature to date.
We describe a case of the uterine liposarcoma arising in a leiomyoma in 48-year-old woman who presented with dysmenorrhea, brownish vaginal discharge, and a rapidly enlarging lower abdominal mass. The tumor emerged from the lower segment of the endometrium and filled the endometrial cavity as a polypoid lesion. The authors of this study documented the adipocyte origin of the tumor with immunohistochemical and electron microscopical studies, the available literature was reviewed and the possible histogenesis was discussed.
We herein report a case of very rare primary liposarcoma arising in a submucosal uterine leiomyoma.
脂肪肉瘤是成人中最常见的软组织肉瘤，然而，子宫发生的脂肪肉瘤极为罕见。事实上，与平滑肌瘤并存的脂肪肉瘤更为罕见，迄今为止英文文献中仅报道过1例。
我们描述了1例48岁女性，其子宫平滑肌瘤发生脂肪肉瘤，表现为痛经、褐色阴道分泌物及下腹部迅速增大的肿块。肿瘤起源于子宫内膜下段，呈息肉样病变充满子宫内膜腔。本研究作者通过免疫组化和电子显微镜研究证实了肿瘤的脂肪细胞起源，回顾了现有文献并讨论了可能的组织发生。
我们在此报告1例罕见的起源于子宫黏膜下平滑肌瘤的原发性脂肪肉瘤病例。
