Yoshihara A, Takano N, Hirotomi T, Ogawa H, Hanada N, Miyazaki H
Division of Preventive Dentistry, Department of Oral Health Science, Graduate School of Medical and Dental Sciences, Niigata University, 2-5274 Gakkocho-Dori, Niigata, 951-8514, Japan.
J Dent Res. 2007 Nov;86(11):1115-9. doi: 10.1177/154405910708601118.
Serum albumin levels are a practical marker of general health status in the elderly and have been used to determine the severity of an underlying disease and the risk for death. This longitudinal study evaluated the relationship between serum albumin levels and root caries. A total of 266 persons with at least 1 tooth at baseline underwent a baseline examination and then annual investigations for 6 years. Multiple linear regression analysis was used to assess the relationship between changes in serum albumin levels and the number of root caries lesions over 6 years, after adjustment for confounding factors. Change in the number of root caries lesions was significantly associated with change in serum albumin concentrations. The standardized coefficient was -0.148 (p = 0.024). We can confirm that serum albumin concentration correlates with root caries events. From these data, we conclude that persons with hypoalbuminemia are at high risk for root caries.
血清白蛋白水平是老年人总体健康状况的一个实用指标，已被用于确定潜在疾病的严重程度和死亡风险。这项纵向研究评估了血清白蛋白水平与根龋之间的关系。共有266名在基线时至少有1颗牙齿的人接受了基线检查，然后进行了为期6年的年度调查。在对混杂因素进行调整后，采用多元线性回归分析来评估6年间血清白蛋白水平变化与根龋损害数量之间的关系。根龋损害数量的变化与血清白蛋白浓度的变化显著相关。标准化系数为-0.148（p = 0.024）。我们可以确认血清白蛋白浓度与根龋事件相关。根据这些数据，我们得出结论，低白蛋白血症患者患根龋的风险很高。
