Yepes-Nuñez Juan José, Morales Cardenas Edison, Gómez-García Carolina, Manco Sepúlveda Madelen, Martínez Lina Marcela, Valero Antonio, McConnell Meghan M
Universidad de los Andes, School of Medicine, Carrera 7 #116-5, 110111, Bogotá, Colombia.
Pulmonology Service, Internal Medicine Section, Fundación Santa Fe de Bogotá University Hospital, Carrera 7b #123-90, 110111, Bogotá, Colombia.
World Allergy Organ J. 2021 Nov 29;14(12):100612. doi: 10.1016/j.waojou.2021.100612. eCollection 2021 Dec.
An instrument to assess Allergic Rhinitis (AR) Health-Related Quality of Life (HRQL) in adult patients was developed in Spain. No validated instrument is currently cross-culturally adapted for use in daily practice to assess HRQL in AR patients in Colombia.
The aim of this study was to evaluate the measurement performance of an AR-HRQL specific questionnaire, ESPRINT-15 (Cuestionario ESPañol de Calidad de Vida en RINiTis), in Colombian adult patients with AR using the Classic Test Theory (CTT) and the Generalizability theory (G-theory) frameworks.
We conducted the cross-cultural adaptation in 2 stages. In stage 1, we evaluated comprehensibility, acceptability, and feasibility of ESPRINT-15 in healthy adults and adult patients with AR. In stage 2, we examined both reliability and validity of ESPRINT-15 scores using CTT and overall reliability applying the G-theory in adult patients with AR.
For feasibility and acceptability, all items showed a higher than 95% level of understanding, and modifications in the original questionnaire were unnecessary. Reliability and validity using CTT showed a high internal consistency (Cronbach's alpha and Mc McDonald's omega = 0.95) and test-retest reliability (scores from 0.70 to 0.76). The overall reliability score using G-theory was 0.75, and G-coefficients scores associated with internal consistency and test-retest reliability measures were 0.96 and 0.61, respectively. Validity using exploratory factor analysis (EFA) identified 2 factors instead of the original ESPRINT-15 4 domains. However, confirmatory factor analysis (CFA) showed good fit regarding the original model.
The proposed cross-cultural adaptation of ESPRINT-15 showed good reliability and validity measures. Additionally, it was easy to use and administer. ESPRINT-15 can be used clinically and for research in Colombian adults' patients with AR. CTT and the G-theory can be used in epidemiological studies to adapt AR-HRQL questionnaires cross-culturally in adult patients with AR.
西班牙研发了一种用于评估成年患者变应性鼻炎（AR）健康相关生活质量（HRQL）的工具。目前尚无经过验证的工具在跨文化环境中适用于哥伦比亚日常实践中评估AR患者的HRQL。
本研究旨在使用经典测试理论（CTT）和概化理论（G理论）框架，评估一种AR-HRQL特异性问卷ESPRINT-15（西班牙语变应性鼻炎生活质量问卷）在哥伦比亚成年AR患者中的测量性能。
我们分两个阶段进行跨文化调适。在第一阶段，我们评估了ESPRINT-15在健康成年人和成年AR患者中的可理解性、可接受性和可行性。在第二阶段，我们使用CTT检验ESPRINT-15评分的信度和效度，并在成年AR患者中应用G理论检验总体信度。
在可行性和可接受性方面，所有条目显示理解水平高于95%，无需对原问卷进行修改。使用CTT的信度和效度显示出较高的内部一致性（Cronbach'sα系数和McDonald'sω系数=0.95）和重测信度（分数在0.70至0.76之间）。使用G理论的总体信度评分为0.75，与内部一致性和重测信度测量相关的G系数评分分别为0.96和0.61。使用探索性因子分析（EFA）进行效度分析时，识别出2个因子，而非原ESPRINT-15的4个领域。然而，验证性因子分析（CFA）显示与原模型拟合良好。
所提议的ESPRINT-15跨文化调适显示出良好的信度和效度测量结果。此外，它易于使用和实施。ESPRINT-15可用于哥伦比亚成年AR患者的临床和研究。CTT和G理论可用于流行病学研究，以对成年AR患者的AR-HRQL问卷进行跨文化调适。
