魁北克铝厂工人的死亡率和癌症患病情况。第3部分：监测1950年1月1日之后首次受雇工人的死亡率。
Mortality and cancer experience of Quebec aluminum reduction plant workers. Part 3: monitoring the mortality of workers first employed after January 1, 1950.
作者信息
Gibbs Graham W, Sevigny Maurice
机构信息
Safety Health Environment International Consultant Corp., Devon, Alberta, Canada, T9G 1Y1.
出版信息
J Occup Environ Med. 2007 Nov;49(11):1269-87. doi: 10.1097/JOM.0b013e3181593da8.
OBJECTIVE
To monitor changes over time in mortality of workers first employed in Quebec aluminum smelters after January 1, 1950 (1951-one cohort).
METHODS
Mortality of cohorts by decade of hire was compared with Quebec and same plant experience before 1950 (1951).
RESULTS
Chronic obstructive pulmonary disease and respiratory cancer (one cohort each) mortality were statistically in excess. In the combined cohorts, standardized mortality ratios exceeded 110 for cancers of esophagus, rectum, and rectosigmoid junction, pancreas, larynx, lung, non-Hodgkin lymphoma, cerebrovascular disease, and asthma. These findings essentially mirrored the experience of pre-1950 workers. There was a significant downward trend in mortality from all causes, lung and bladder cancer.
CONCLUSIONS
Statistically significant improvements were found in mortality from all causes combined, from cancer and from cancer of the lung and bladder. Slightly increased mortality continues from certain other causes.
目的
监测1950年1月1日之后首次受雇于魁北克铝冶炼厂的工人（1951年为一个队列）的死亡率随时间的变化。
方法
将按雇佣年代划分的队列死亡率与1950年（1951年）之前魁北克及同一工厂的情况进行比较。
结果
慢性阻塞性肺疾病和呼吸道癌症（各一个队列）的死亡率在统计学上过高。在合并队列中，食管、直肠和直肠乙状结肠交界处、胰腺、喉、肺、非霍奇金淋巴瘤、脑血管疾病和哮喘的标准化死亡率超过110。这些发现基本上反映了1950年之前工人的情况。所有原因、肺癌和膀胱癌的死亡率呈显著下降趋势。
结论
在所有原因合并、癌症以及肺癌和膀胱癌的死亡率方面发现了具有统计学意义的改善。某些其他原因导致的死亡率仍略有上升。
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