1969 - 2022年全球工人队列中肺癌风险与多环芳烃职业暴露情况
Risk of Lung Cancer and Occupational Exposure to Polycyclic Aromatic Hydrocarbons Among Workers Cohorts - Worldwide, 1969-2022.
作者信息
Yuan Huige, Wang Yanhua, Duan Huawei
机构信息
National Institute for Occupational Health and Poison Control, Chinese Center for Disease Control and Prevention, Beijing, China.
出版信息
China CDC Wkly. 2022 Apr 29;4(17):364-369. doi: 10.46234/ccdcw2022.085.
WHAT IS ALREADY KNOWN ABOUT THIS TOPIC?: Lung cancer has a high mortality, resulting in a severe disease burden. Polycyclic aromatic hydrocarbons (PAHs) are definitive carcinogen to human, and occupational exposure to PAHs is associated with lung cancer.
WHAT IS ADDED BY THIS REPORT?: We analyzed the cancer cases from cohort studies on various PAHs exposed workers in China and other countries, calculated the quantitative risk of lung cancer based on meta-analyses, and confirmed the increased risk from lung cancer in selected PAHs exposed occupations.
WHAT ARE THE IMPLICATIONS FOR PUBLIC HEALTH PRACTICES?: There is a clear need to prevent lung cancer on a wide range of PAHs-related occupations in China and around the world. It is crucial to establish guidelines for improving the monitoring on exposure and health promotion in related working environments.
关于该主题已知的信息有哪些？：肺癌死亡率高，导致严重的疾病负担。多环芳烃（PAHs）是人类明确的致癌物，职业接触多环芳烃与肺癌有关。
本报告新增了哪些内容？：我们分析了来自中国和其他国家各类接触多环芳烃工人队列研究中的癌症病例，基于荟萃分析计算了肺癌的定量风险，并证实了在选定的接触多环芳烃职业中肺癌风险增加。
对公共卫生实践有何启示？：在中国和全球范围内，显然有必要在广泛的与多环芳烃相关的职业中预防肺癌。制定指南以加强对相关工作环境中接触情况的监测和健康促进至关重要。
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