Nóbrega Ana Caline, Rodrigues Bernardo, Melo Ailton
Division of Neurology and Epidemiology, Federal University of Bahia, Brazil.
Clin Neurol Neurosurg. 2008 Feb;110(2):117-9. doi: 10.1016/j.clineuro.2007.09.011. Epub 2007 Nov 19.
We studied the frequency of silent laryngeal penetration or silent aspiration (SLP/SA) in Parkinson's disease (PD) patients with diurnal sialorrhea.
In 19 consecutive PD patients with diurnal sialorrhea, swallow was evaluated using the videofluoroscopy analysis. Data were analysed to determine the frequency of aspiration and its relationship with the severity of sialorrhea.
All patients were classified in the Hoehn and Yahr stages between 2 and 5. SLP/SA was observed in 21% of patients and the score of sialorrhea in the group with SLP/SA was 8.0+/-0.81, while in the group with no SLP/SA was 6.46+/-1.06 (p=0.02).
SLP/SA is a frequent morbidity in PD patients, its risk is higher in later stages of disease and in those patients with severe sialorrhea. However, prospective and controlled studies of follow up will be necessary to determine the prognosis and management in this group of patients.
我们研究了患有日间流涎的帕金森病（PD）患者中沉默性喉穿透或沉默性误吸（SLP/SA）的发生率。
对19例连续的患有日间流涎的PD患者，使用视频荧光透视分析评估吞咽情况。分析数据以确定误吸的发生率及其与流涎严重程度的关系。
所有患者的Hoehn和Yahr分期在2至5期之间。21%的患者观察到SLP/SA，有SLP/SA组的流涎评分是8.0±0.81，而无SLP/SA组是6.46±1.06（p=0.02）。
SLP/SA在PD患者中是一种常见的病症，在疾病后期以及那些流涎严重的患者中风险更高。然而，需要进行前瞻性和对照性的随访研究来确定该组患者的预后和治疗方法。
