Cavazos-Rehg Patricia A, Spitznagel Edward L, Bucholz Kathleen K, Norberg Karen, Reich Wendy, Nurnberger John, Hesselbrock Victor, Kramer John, Kuperman Sam, Bierut Laura Jean
Washington University in St. Louis, St. Louis, Missouri, USA.
Alcohol Clin Exp Res. 2007 Dec;31(12):2046-52. doi: 10.1111/j.1530-0277.2007.00537.x.
Heavy drinking is associated with an increased number of sexual partners. This study examined the extent to which alcohol dependence and conduct disorder are associated with the number of sexual partners and membership in a risk group of having a high number of sexual partners (10 or more).
Data were obtained by personal interview from 601 relatives (aged 18 to 25 years) of alcohol-dependent probands who participated in the Collaborative Study on the Genetics of Alcoholism (COGA) project. Analyses examined the independent contribution of problem drinking (defined as having at least one symptom of DSM-IV alcohol dependence) and alcohol dependence, some conduct problems (defined as having at least one symptom of DSM-IV conduct disorder), conduct disorder, family status (defined as whether participant lived with both biological parents during childhood), educational attainment, gender, race, age at first intercourse, and age at time of interview to the number of sexual partners and to having 10 or more sexual partners.
After controlling for other variables, alcohol dependence, problem drinking, race, age at first intercourse, and age at time of interview were significantly associated with number of sexual partners. The risk for having 10 or more sexual partners rose substantially for those who were alcohol dependent (OR = 2.5, 1.3-4.5, p = 0.004) and those with conduct disorder (OR = 1.8, 1.0-3.3, p = 0.041) after controlling for other variables. There is also a trend toward problem drinking and some conduct problems being associated with the risk of having 10 or more sexual partners though this did not reach statistical significance.
These analyses demonstrate that alcohol-dependent individuals and those with conduct disorder are at risk for increased number of sexual partners (10 or more). Sexually transmitted disease prevention efforts should target individuals with these two conditions to help decrease high risk sexual behaviors.
大量饮酒与性伴侣数量增加有关。本研究调查了酒精依赖和品行障碍与性伴侣数量以及性伴侣数量较多（10个或更多）的风险群体成员身份之间的关联程度。
通过对参与酒精中毒遗传学合作研究（COGA）项目的酒精依赖先证者的601名亲属（年龄在18至25岁之间）进行个人访谈获取数据。分析考察了问题饮酒（定义为具有至少一项DSM-IV酒精依赖症状）、酒精依赖、一些品行问题（定义为具有至少一项DSM-IV品行障碍症状）、品行障碍、家庭状况（定义为参与者童年时期是否与双亲同住）、教育程度、性别、种族、初次性交年龄以及访谈时年龄对性伴侣数量和拥有10个或更多性伴侣的独立影响。
在控制其他变量后，酒精依赖、问题饮酒、种族、初次性交年龄以及访谈时年龄与性伴侣数量显著相关。在控制其他变量后，酒精依赖者（OR = 2.5，1.3 - 4.5，p = 0.004）和患有品行障碍者（OR = 1.8，1.0 - 3.3，p = 0.041）拥有10个或更多性伴侣的风险大幅上升。虽然问题饮酒和一些品行问题与拥有10个或更多性伴侣的风险之间也存在一种趋势，但未达到统计学显著性。
这些分析表明，酒精依赖个体和患有品行障碍的个体面临性伴侣数量增加（10个或更多）的风险。性传播疾病预防工作应针对患有这两种情况的个体，以帮助减少高风险性行为。
