Harz C, Henkel T O, Köhrmann K U, Pimentel F, Alken P, Manegold B C
Abteilung für Endoskopie, Fakultät für Klinische Medizin, Universität Heidelberg, Mannheim, Federal Republic of Germany.
Surg Endosc. 1991;5(4):196-9. doi: 10.1007/BF02653263.
Endoscopic treatment of bile duct stones is currently successful in 86% of patients. We prospectively studied the efficacy and complication rate of extracorporeal shock-wave lithotripsy (ESWL) of problematic bile duct stones combined with endoscopy. When stone removal was not possible, patients were subjected to ESWL. Fragmented stones were removed endoscopically. During 1 year, 220 patients presenting with choledocholithiasis were diagnosed and 188 were successfully treated endoscopically. In all, 3 subjects received alternative treatment and the remaining 29 (13%) constituted our study group; 19 (65%) were women and the mean age was 76.7 years. Overall, 22 (76%) were high-risk patients; 23 (79%) were jaundiced and 9 (31%) had cholangitis at admission. The most frequent indication for ESWL was stone size. Stone fragmentation was achieved in 80% of cases. Complications were mild and were managed conservatively. No patient died. Complete stone clearance was possible in 23 (80%) cases. The association of ESWL and endoscopy enhanced the success rate of endoscopic stone clearance from 86% to 96%. During the same period, open surgery was performed in 4 cases for residual common bile duct (CBD) stones and in 32 cases in association with simultaneous cholecystectomy.
目前,内镜治疗胆管结石在86%的患者中取得成功。我们前瞻性地研究了体外冲击波碎石术(ESWL)联合内镜治疗疑难胆管结石的疗效和并发症发生率。当无法通过内镜取石时,对患者进行ESWL治疗。将破碎的结石通过内镜取出。在1年时间里,共诊断出220例胆总管结石患者,其中188例通过内镜成功治疗。共有3例患者接受了其他治疗,其余29例(13%)构成我们的研究组;19例(65%)为女性,平均年龄为76.7岁。总体而言,22例(76%)为高危患者;23例(79%)有黄疸,9例(31%)入院时患有胆管炎。ESWL最常见的适应证是结石大小。在80%的病例中实现了结石破碎。并发症较轻,通过保守治疗处理。无患者死亡。23例(80%)病例实现了结石完全清除。ESWL与内镜联合使用将内镜取石成功率从86%提高到了96%。同期,4例因残余胆总管结石进行了开放手术,32例在同期行胆囊切除术时进行了开放手术。