开角型青光眼与视网膜中央静脉非阻塞性病变——孰因孰果？
Open angle glaucoma and non-central retinal vein occlusion--the chicken or the egg?
作者信息
Lindblom B
机构信息
Department of Ophthalmology, Institute of Clinical Neuroscience, Göteborg University, Sweden.
出版信息
Acta Ophthalmol Scand. 1998 Jun;76(3):329-33. doi: 10.1034/j.1600-0420.1998.760315.x.
PURPOSE
To determine whether non-central retinal vein occlusion (nCRVO) or open angle glaucoma (OAG) is the primary event in eyes suffering from both diseases.
METHODS
The study has two parts. The first is a retrospective survey of a clinical glaucoma database. In eyes with OAG and nCRVO, the temporal relationship between the conditions was determined when possible. The second part is a ten-year follow-up study of eyes with isolated nCRVO.
RESULTS
Study 1: Among 576 OAG patients, 25 (4.3%) had nCRVO. In all eyes except one, OAG occurred before nCRVO. Almost without exception a vein on the optic disk or at the disk margin was occluded. Study 2: Most eyes with isolated nCRVO had an occluded vein at a retinal artery-vein crossing. Only one of 34 patients had developed OAG after ten years.
CONCLUSIONS
This study suggests that OAG in most eyes is the primary event. nCRVO had different characteristics in eyes with OAG compared to eyes without OAG.
目的
确定在同时患有非中心性视网膜静脉阻塞（nCRVO）和开角型青光眼（OAG）的眼中，哪种疾病是原发事件。
方法
本研究分为两部分。第一部分是对一个临床青光眼数据库的回顾性调查。对于患有OAG和nCRVO的眼睛，尽可能确定两种病症之间的时间关系。第二部分是对孤立性nCRVO患者进行为期十年的随访研究。
结果
研究1：在576例OAG患者中，25例（4.3%）患有nCRVO。除一只眼睛外，在所有眼睛中，OAG均先于nCRVO出现。几乎无一例外，视盘或视盘边缘的一条静脉发生了阻塞。研究2：大多数孤立性nCRVO患者的视网膜动静脉交叉处有一条静脉阻塞。34例患者中只有1例在十年后发展为OAG。
结论
本研究表明，大多数眼中OAG是原发事件。与未患OAG的眼睛相比，患有OAG的眼睛中的nCRVO具有不同的特征。
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