Rouse A R, Gmitro A F
Department of Radiology and the Optical Sciences Center, University of Arizona, Tucson, Arizona 85724, USA.
Opt Lett. 2000 Dec 1;25(23):1708-10. doi: 10.1364/ol.25.001708.
The concept of a multispectral confocal microscope for in vivo imaging is introduced. To demonstrate the concept we modified a slit-scan fluorescence confocal microendoscope incorporating a fiber-optic catheter for in vivo imaging to record multispectral images. The system was designed to examine cellular structures during optical biopsy and to exploit the diagnostic information contained within the spectral domain. Preliminary experiments were carried out in phantoms and cell cultures to demonstrate the potential of the technique.
介绍了用于体内成像的多光谱共聚焦显微镜的概念。为了验证这一概念，我们对一台用于体内成像的、结合了光纤导管的狭缝扫描荧光共聚焦微型内窥镜进行了改进，以记录多光谱图像。该系统旨在在光学活检过程中检查细胞结构，并利用光谱域中包含的诊断信息。在模型和细胞培养物中进行了初步实验，以证明该技术的潜力。
