树突状细胞亚群之间的分工、可塑性及相互作用
Division of labor, plasticity, and crosstalk between dendritic cell subsets.
作者信息
Pulendran Bali, Tang Hua, Denning Timothy L
机构信息
Emory Vaccine Center, 954 Gatewood Road, Atlanta, GA 30329, USA.
出版信息
Curr Opin Immunol. 2008 Feb;20(1):61-7. doi: 10.1016/j.coi.2007.10.009. Epub 2007 Dec 21.
Abstract
For years, dendritic cell (DC) biologists have oscillated between two seemingly antagonistic ideas: functional specialization (division of labor) of DC subsets and plasticity (multitasking). More recently, a third hypothesis is gathering support: crosstalk between functionally distinct DC subsets. This reveals a previously unappreciated hierarchy of organization within the DC system, and provides a conceptual framework to understand how cooperation between functionally distinct, yet plastic, DC subsets can shape adaptive immunity and immunological memory. Here we review the recent advances in this area.
摘要
多年来，树突状细胞（DC）生物学家一直在两个看似相互对立的观点之间摇摆不定：DC亚群的功能特化（分工）和可塑性（多功能性）。最近，第三种假说正在获得支持：功能不同的DC亚群之间的相互作用。这揭示了DC系统中一个以前未被重视的组织层次结构，并提供了一个概念框架，以理解功能不同但具有可塑性的DC亚群之间的合作如何塑造适应性免疫和免疫记忆。在这里，我们综述了该领域的最新进展。
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本文引用的文献
1
Regulatory T cells and infection: a dangerous necessity.调节性T细胞与感染：一种危险的必然需求。
Nat Rev Immunol. 2007 Nov;7(11):875-88. doi: 10.1038/nri2189.
2
Recognition of microorganisms and activation of the immune response.微生物的识别与免疫反应的激活。
Nature. 2007 Oct 18;449(7164):819-26. doi: 10.1038/nature06246.
3
The science of adjuvants.佐剂科学。
Expert Rev Vaccines. 2007 Oct;6(5):673-84. doi: 10.1586/14760584.6.5.673.
4
Taking dendritic cells into medicine.将树突状细胞应用于医学。
Nature. 2007 Sep 27;449(7161):419-26. doi: 10.1038/nature06175.
5
Innate recognition of viruses.病毒的天然识别
Immunity. 2007 Sep;27(3):370-83. doi: 10.1016/j.immuni.2007.08.012.
6
Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses.固有层巨噬细胞和树突状细胞分别诱导调节性T细胞反应和产生白细胞介素17的T细胞反应。
Nat Immunol. 2007 Oct;8(10):1086-94. doi: 10.1038/ni1511. Epub 2007 Sep 16.
7
Dendritic cell subsets in health and disease.健康与疾病中的树突状细胞亚群
Immunol Rev. 2007 Oct;219:118-42. doi: 10.1111/j.1600-065X.2007.00551.x.
8
Th17: the third member of the effector T cell trilogy.辅助性T细胞17：效应T细胞三部曲的第三个成员。
Curr Opin Immunol. 2007 Dec;19(6):652-7. doi: 10.1016/j.coi.2007.07.020. Epub 2007 Sep 4.
9
Cutting edge: Peyer's patch plasmacytoid dendritic cells (pDCs) produce low levels of type I interferons: possible role for IL-10, TGFbeta, and prostaglandin E2 in conditioning a unique mucosal pDC phenotype.前沿：派尔集合淋巴结浆细胞样树突状细胞（pDC）产生低水平的I型干扰素：白细胞介素-10、转化生长因子β和前列腺素E2在塑造独特的黏膜pDC表型中的可能作用。
J Immunol. 2007 Sep 1;179(5):2690-4. doi: 10.4049/jimmunol.179.5.2690.
10
All-trans retinoic acid mediates enhanced T reg cell growth, differentiation, and gut homing in the face of high levels of co-stimulation.在存在高水平共刺激的情况下，全反式维甲酸介导调节性T细胞的生长、分化增强及向肠道归巢。
J Exp Med. 2007 Aug 6;204(8):1765-74. doi: 10.1084/jem.20070719. Epub 2007 Jul 9.
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