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Cultural differences in rates of alcoholism.酗酒发生率中的文化差异。
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A behavioral-genetic perspective on children of alcoholics.从行为遗传学角度看酗酒者的子女。
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Alcoholism: theory, problem and challenge. II. Reinforcement theory and the dynamics of alcoholism.酗酒:理论、问题与挑战。二、强化理论与酗酒的动态变化
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Effects of acute social stress on alcohol consumption in healthy subjects.急性社会应激对健康受试者酒精摄入量的影响。
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Etiologic connections among substance dependence, antisocial behavior, and personality: modeling the externalizing spectrum.物质依赖、反社会行为和人格之间的病因学联系:对外显谱系进行建模
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Alcohol abuse and dependence among U.S. college students.美国大学生中的酒精滥用与酒精依赖问题。
J Stud Alcohol. 2002 May;63(3):263-70. doi: 10.15288/jsa.2002.63.263.
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Biphasic alcohol response differs in heavy versus light drinkers.重度饮酒者与轻度饮酒者的双相酒精反应有所不同。
Alcohol Clin Exp Res. 2002 Jun;26(6):827-35.
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Effects of stress and alcohol on subjective state in humans.压力和酒精对人类主观状态的影响。
Alcohol Clin Exp Res. 2002 Jun;26(6):818-26. doi: 10.1097/00000374-200206000-00011.
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Trends in college binge drinking during a period of increased prevention efforts. Findings from 4 Harvard School of Public Health College Alcohol Study surveys: 1993-2001.在预防力度加大期间大学生酗酒的趋势。来自哈佛公共卫生学院4次大学生酒精研究调查的结果:1993 - 2001年。
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刺激性酒精效应会引发饮酒过程中的即时饮酒行为。

Stimulant alcohol effects prime within session drinking behavior.

作者信息

Corbin William R, Gearhardt Ashley, Fromme Kim

机构信息

Department of Psychology, Yale University, 2 Hillhouse Ave, New Haven, CT 06520-8205, USA.

出版信息

Psychopharmacology (Berl). 2008 Apr;197(2):327-37. doi: 10.1007/s00213-007-1039-x. Epub 2007 Dec 15.

DOI:10.1007/s00213-007-1039-x
PMID:18084744
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3039601/
Abstract

RATIONALE

Individual differences in subjective alcohol effects have been shown to differ by risk status (e.g., family history of alcoholism) and to predict future risk for alcohol-related problems. Presumably, individual differences in both stimulant and sedative responses affect the rewarding value of drinking which, in turn, impacts future drinking behavior. Although plausible, this theoretical model is largely untested.

OBJECTIVES

The current study attempted to provide experimental evidence for the impact of subjective alcohol responses on within session drinking behavior.

MATERIALS AND METHODS

Using a placebo-controlled between-subjects alcohol administration paradigm, experiences and evaluations of stimulant and sedative alcohol effects (after a target dose of 0.06 g%) were assessed as predictors of ad-libitum consumption in the context of anticipatory stress.

RESULTS

Analyses indicated that an initial dose of alcohol increased experiences of both stimulation and sedation although stimulant effects were evaluated much more positively. In addition, stimulant effects after a priming dose predicted further consumption, whereas sedative effects did not.

CONCLUSIONS

At least among moderate to heavy drinking college students, stimulant alcohol effects are more reinforcing and predict within session drinking behavior under social stress. Increased attention should be given to stimulant alcohol effects as a risk factor for excessive consumption in this population. Incorporating information about stimulant alcohol effects in prevention and intervention programs may also be important if additional research supports the current results.

摘要

理论依据

主观酒精效应的个体差异已被证明因风险状态(如酒精中毒家族史)而异,并能预测未来与酒精相关问题的风险。据推测,兴奋和镇静反应的个体差异都会影响饮酒的奖赏价值,进而影响未来的饮酒行为。尽管这一理论模型看似合理,但在很大程度上尚未得到验证。

目的

本研究试图为酒精主观反应对饮酒期间饮酒行为的影响提供实验证据。

材料与方法

采用安慰剂对照的组间酒精给药范式,在预期应激的背景下,评估兴奋和镇静酒精效应(目标剂量为0.06 g%后)的体验和评价,作为随意饮酒量的预测指标。

结果

分析表明,初始剂量的酒精会增加兴奋和镇静的体验,尽管对兴奋效应的评价更为积极。此外,预充剂量后的兴奋效应可预测进一步的饮酒量,而镇静效应则不然。

结论

至少在中度至重度饮酒的大学生中,酒精的兴奋效应更具强化作用,并能预测社交压力下饮酒期间的饮酒行为。应更多地关注酒精兴奋效应,将其作为该人群过度饮酒的一个风险因素。如果更多的研究支持当前结果,那么在预防和干预项目中纳入有关酒精兴奋效应的信息也可能很重要。