Goldberg David J, Fazeli Amin, Berlin Alexander L
Skin Laser and Surgery Specialists of NY/NJ, New York, New York 10016, USA.
Dermatol Surg. 2008 Feb;34(2):204-9; discussion 209. doi: 10.1111/j.1524-4725.2007.34038.x. Epub 2007 Dec 17.
Cellulite is seen in more than 85% of postpubertal women. Recent studies show that bipolar radiofrequency and low-level laser devices can produce mild skin tightening of cellulite.
The primary objective was to determine if a novel unipolar, more deeply penetrating, radiofrequency device can promote better skin tightening with fewer treatments than is seen with previously described devices. The secondary objective was to determine if such a deeply penetrating device produced undesired effects on lipid metabolism.
Thirty subjects, with Nurnberger-Muller Scale III-IV upper thigh cellulite, were entered into the study. All were treated, every other week, with a unipolar radiofrequency device for a total of six treatments. Subjects were evaluated before and 6 months after treatment with clinical photographs, clinical measurements, biopsies, MRIs, and blood lipid evaluations.
Twenty-seven subjects showed evidence of clinical improvement. The mean decrease in leg circumference was 2.45 cm. Histologic changes showed dermal fibrosis of the upper dermis. No MRI or lipid abnormalities were noted.
Upper thigh skin cellulite can be improved with a new unipolar radiofrequency device. Histologic changes suggest skin tightening as the method of improvement. No undesired complications of the skin or lipid metabolism were noted.
超过85%的青春期后女性存在橘皮组织。最近的研究表明，双极射频和低强度激光设备可使橘皮组织产生轻度皮肤紧致效果。
主要目的是确定一种新型单极、穿透性更强的射频设备是否能以比先前所述设备更少的治疗次数促进更好的皮肤紧致。次要目的是确定这种穿透性强的设备是否会对脂质代谢产生不良影响。
30名患有诺恩伯格-米勒量表III-IV级大腿上部橘皮组织的受试者进入该研究。所有受试者每隔一周接受一次单极射频设备治疗，共治疗六次。在治疗前和治疗后6个月，通过临床照片、临床测量、活检、磁共振成像和血脂评估对受试者进行评估。
27名受试者显示出临床改善的迹象。腿部周长平均减少2.45厘米。组织学变化显示真皮上层出现真皮纤维化。未发现磁共振成像或脂质异常。
一种新型单极射频设备可改善大腿上部皮肤橘皮组织。组织学变化表明皮肤紧致是改善的方式。未发现皮肤或脂质代谢的不良并发症。
