一项使用1440纳米掺钕钇铝石榴石波长激光及侧向发射光纤治疗橘皮组织的多中心研究。
A Multicenter Study for Cellulite Treatment Using a 1440-nm Nd:YAG Wavelength Laser with Side-Firing Fiber.
作者信息
DiBernardo Barry E, Sasaki Gordon H, Katz Bruce E, Hunstad Joseph P, Petti Christine, Burns A Jay
机构信息
Dr DiBernardo is an Associate Clinical Professor of Plastic and Reconstructive Surgery, University of Medicine and Dentistry of New Jersey, Newark, NJ, USA. Dr Sasaki is a Clinical Professor of Plastic Surgery, Loma Linda University Medical School, Loma Linda, CA, USA. Dr Katz is a Clinical Professor of Dermatology, Mount Sinai School of Medicine, New York, NY, USA. Dr Hunstad is an Associate Clinical Professor, Division of Plastic Surgery, University of North Carolina at Chapel Hill; and Section Head of Plastic Surgery, Carolinas Medical Ctr., University Hospital, Charlotte, NC, USA. Dr Petti is a plastic surgeon in private practice in Torrance, CA, USA. Dr Burns is an Assistant Professor of Plastic Surgery, University of Texas Southwestern Medical School, Dallas, TX, USA.
出版信息
Aesthet Surg J. 2016 Mar;36(3):335-43. doi: 10.1093/asj/sjv203.
BACKGROUND
Treatment of cellulite using a 1440-nm YAG wavelength laser with side-firing fiber has proven safe and effective, lasting at least 6 months.
OBJECTIVES
The authors evaluate the safety and efficacy of a single, subdermal procedure to treat the underlying structure of cellulite for at least 1 year.
METHODS
Fifty-seven patients underwent a 3-step cellulite treatment with a 1440-nm Nd:YAG laser with a side-firing fiber and temperature-sensing cannula. Efficacy was measured by the blinded evaluators to distinguish baseline photos from those taken at 12 months posttreatment, with results on a 5-point, 2-category ordinal photonumeric scale when comparing baseline photos to 12 months posttreatment. Subject and physician satisfaction was assessed based on completion of a satisfaction survey. Adverse events (AE) were recorded throughout the study. Twelve month data were analyzed and compared to 6 month data.
RESULTS
Evaluators chose baseline photographs 97% on average from 6 (-1, +2) months and 91% from the 12 (-3, +2) months posttreatment photographs. At 6 (-1, +2) months, the average improvement score was 1.7 for dimples and 1.1 for contour irregularities. At 12 (-3, +2) months, the average improvement score was 1.4 for dimples and 1.0 for contour irregularities. The average satisfaction score for the physician was 5.6 and the patient was 5.3 on a 6-point scale.
CONCLUSIONS
A single, 3-step, minimally invasive laser treatment using a 1440-nm Nd:YAG laser, side-firing fiber, and temperature-sensing cannula to treat the underlying structure of cellulite proved to be safe and maintained effectiveness at least 1 year post treatment. LEVEL OF EVIDENCE 2: Therapeutic.
背景
使用波长为1440纳米的钇铝石榴石（YAG）激光及侧射光纤治疗橘皮组织已被证明是安全有效的，效果至少可持续6个月。
目的
作者评估单次皮下手术治疗橘皮组织深层结构至少1年的安全性和有效性。
方法
57例患者接受了使用波长为1440纳米的掺钕钇铝石榴石（Nd:YAG）激光、侧射光纤和温度传感套管的三步橘皮组织治疗。由盲法评估者测量疗效，以区分基线照片与治疗后12个月拍摄的照片，在比较基线照片与治疗后12个月照片时，结果采用5分、2类序贯光子数值量表。根据满意度调查的完成情况评估受试者和医生的满意度。在整个研究过程中记录不良事件（AE）。分析12个月的数据并与6个月的数据进行比较。
结果
评估者平均有97%的情况下从治疗后6（-1，+2）个月的照片中选择基线照片，91%的情况下从治疗后12（-3，+2）个月的照片中选择。在6（-1，+2）个月时，酒窝的平均改善评分为1.7，轮廓不规则的平均改善评分为1.1。在12（-3，+2）个月时，酒窝的平均改善评分为1.4，轮廓不规则的平均改善评分为1.0。在6分制量表上，医生的平均满意度评分为5.6，患者为5.3。
结论
使用波长为1440纳米的Nd:YAG激光、侧射光纤和温度传感套管进行单次、三步、微创激光治疗橘皮组织深层结构被证明是安全的，且治疗后至少1年仍保持有效性。证据级别2：治疗性。
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