腹侧视觉皮层中的先天与后天因素：一项双胞胎的功能磁共振成像研究
Nature versus nurture in ventral visual cortex: a functional magnetic resonance imaging study of twins.
作者信息
Polk Thad A, Park Joonkoo, Smith Mason R, Park Denise C
机构信息
Department of Psychology, University of Michigan, Ann Arbor, Michigan 48109, USA.
出版信息
J Neurosci. 2007 Dec 19;27(51):13921-5. doi: 10.1523/JNEUROSCI.4001-07.2007.
Abstract
Using functional magnetic resonance imaging, we estimated neural activity in twins to study genetic influences on the cortical response to categories of visual stimuli (faces, places, and pseudowords) that are known to elicit distinct patterns of activity in ventral visual cortex. The neural activity patterns in monozygotic twins were significantly more similar than in dizygotic twins for the face and place stimuli, but there was no effect of zygosity for pseudowords (or chairs, a control category). These results demonstrate that genetics play a significant role in determining the cortical response to faces and places, but play a significantly smaller role (if any) in the response to orthographic stimuli.
摘要
我们使用功能磁共振成像技术，估算双胞胎的神经活动，以研究基因对视觉刺激类别（面部、地点和假词）的皮质反应的影响，这些视觉刺激已知会在腹侧视觉皮层引发不同的活动模式。对于面部和地点刺激，同卵双胞胎的神经活动模式比异卵双胞胎的显著更相似，但对于假词（或椅子，一个对照类别），合子性没有影响。这些结果表明，基因在决定对面部和地点的皮质反应中起重要作用，但在对正字法刺激的反应中起的作用显著较小（如果有作用的话）。
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本文引用的文献
1
Early commitment of neural substrates for face recognition.
Cogn Neuropsychol. 2000 Feb 1;17(1):117-23. doi: 10.1080/026432900380526.
2
Visual word processing and experiential origins of functional selectivity in human extrastriate cortex.
Proc Natl Acad Sci U S A. 2007 May 22;104(21):9087-92. doi: 10.1073/pnas.0703300104. Epub 2007 May 14.
3
Expert face processing requires visual input to the right hemisphere during infancy.
Nat Neurosci. 2003 Oct;6(10):1108-12. doi: 10.1038/nn1121. Epub 2003 Sep 7.
4
An automated method for neuroanatomic and cytoarchitectonic atlas-based interrogation of fMRI data sets.
Neuroimage. 2003 Jul;19(3):1233-9. doi: 10.1016/s1053-8119(03)00169-1.
5
Developmental dyslexia: genetic dissection of a complex cognitive trait.
Nat Rev Neurosci. 2002 Oct;3(10):767-80. doi: 10.1038/nrn936.
6
Neural specialization for letter recognition.
J Cogn Neurosci. 2002 Feb 15;14(2):145-59. doi: 10.1162/089892902317236803.
7
Functional MRI evidence for an abstract, not perceptual, word-form area.
J Exp Psychol Gen. 2002 Mar;131(1):65-72. doi: 10.1037//0096-3445.131.1.65.
8
Genetic influences on brain structure.
Nat Neurosci. 2001 Dec;4(12):1253-8. doi: 10.1038/nn758.
9
Distributed and overlapping representations of faces and objects in ventral temporal cortex.
Science. 2001 Sep 28;293(5539):2425-30. doi: 10.1126/science.1063736.
10
Expertise for cars and birds recruits brain areas involved in face recognition.
Nat Neurosci. 2000 Feb;3(2):191-7. doi: 10.1038/72140.
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