Polk Thad A, Park Joonkoo, Smith Mason R, Park Denise C
Department of Psychology, University of Michigan, Ann Arbor, Michigan 48109, USA.
J Neurosci. 2007 Dec 19;27(51):13921-5. doi: 10.1523/JNEUROSCI.4001-07.2007.
Using functional magnetic resonance imaging, we estimated neural activity in twins to study genetic influences on the cortical response to categories of visual stimuli (faces, places, and pseudowords) that are known to elicit distinct patterns of activity in ventral visual cortex. The neural activity patterns in monozygotic twins were significantly more similar than in dizygotic twins for the face and place stimuli, but there was no effect of zygosity for pseudowords (or chairs, a control category). These results demonstrate that genetics play a significant role in determining the cortical response to faces and places, but play a significantly smaller role (if any) in the response to orthographic stimuli.
我们使用功能磁共振成像技术，估算双胞胎的神经活动，以研究基因对视觉刺激类别（面部、地点和假词）的皮质反应的影响，这些视觉刺激已知会在腹侧视觉皮层引发不同的活动模式。对于面部和地点刺激，同卵双胞胎的神经活动模式比异卵双胞胎的显著更相似，但对于假词（或椅子，一个对照类别），合子性没有影响。这些结果表明，基因在决定对面部和地点的皮质反应中起重要作用，但在对正字法刺激的反应中起的作用显著较小（如果有作用的话）。
