Gregório Marcelo Gervilla, Jacomelli Márcia, Figueiredo Adelaide C, Cahali Michel Burihan, Pedreira Wilson Leite, Lorenzi Filho Geraldo
Respiratory Endoscopy Service, University of São Paulo Medical School.
Braz J Otorhinolaryngol. 2007 Sep-Oct;73(5):618-22. doi: 10.1016/s1808-8694(15)30121-x.
The use of nasopharyngoscopy during the application of intrathoracic pressure (Müller maneuver) is frequently employed to establish the site of upper airway obstruction. The Müller maneuver, however, is used when the patient is awake and therefore may not correlate with obstruction occurring during sleep.
To compare the degree of pharyngeal obstruction in the retropalatal and retroglossal regions during the Müller maneuver versus induced sleep using nasopharyngoscopy.
A prospective, case series study.
Eight patients (three males, five females), with a mean age of 48.6 +/- 9.2 year, underwent nasopharyngoscopy to assess airway anatomy and function during the Müller maneuver while awake and during sleep induced by drip infusion of Midazolam.
Retropalatal obstruction was similar during the Müller maneuver and sleep (mean + standard deviation = 3.13 +/- 0.99 and 2.75 +/- 0.46, p= 0.234). Retroglossal obstruction was significantly lower during Müller maneuver compared to sleep (mean + standard deviation 0.63 +/- 1.06 and 2.63 +/- 1.30, respectively, p= 0.005).
The sleep inducing method was safe under the monitored conditions of this study, and detected more retroglossal obstruction than the Müller maneuver.
在施加胸腔内压力(米勒动作)期间使用鼻咽镜检查常用于确定上气道阻塞的部位。然而,米勒动作是在患者清醒时使用的,因此可能与睡眠期间发生的阻塞情况不相关。
使用鼻咽镜检查比较米勒动作与诱导睡眠期间腭后和舌后区域的咽部阻塞程度。
一项前瞻性病例系列研究。
8例患者(3例男性,5例女性),平均年龄48.6±9.2岁,接受鼻咽镜检查,以评估清醒时米勒动作期间以及咪达唑仑静脉滴注诱导睡眠期间的气道解剖结构和功能。
腭后阻塞在米勒动作和睡眠期间相似(平均值+标准差=3.13±0.99和2.75±0.46,p = 0.234)。与睡眠相比,米勒动作期间舌后阻塞明显更低(平均值+标准差分别为0.63±1.06和2.63±1.30,p = 0.005)。
在本研究的监测条件下,睡眠诱导方法是安全的,并且比米勒动作检测到更多的舌后阻塞。