Hug Kristina
Department of Medical Ethics, Lund University, Lund, Sweden.
Fertil Steril. 2008 Feb;89(2):263-77. doi: 10.1016/j.fertnstert.2007.09.017. Epub 2007 Dec 31.
To review publications regarding possible donation of surplus embryos for medical research.
Review of 67 scientific publications in this field up through January 2007.
Summary of factors influencing prospective donors' motivation to donate or not donate their surplus embryos for medical research.
RESULT(S): Presentation of the findings of studies regarding the need and availability of quality human embryos for stem-cell research, discussion of the use of nonoptimal quality embryos for research, and presentation of the findings of several studies regarding the attitudes of fertility patients toward embryo donation for research in general and for stem-cell research in particular. In addition, discussion of the difficulty of such decision making and presentation of suggested strategies to facilitate reasoned, reflective, and timely decisions by prospective donors.
CONCLUSION(S): The major part of this article presents the findings of studies regarding the factors influencing couples' decisions about whether or not to donate surplus embryos for research. Research purpose, treatment stage, embryo quality, religious beliefs, and altruism appear to be important for donation. Being at the beginning of treatment, not knowing the aim of medical research, or having good-quality embryos appear to motivate those who answer that they do not want to donate.
回顾关于多余胚胎用于医学研究的潜在捐赠的相关文献。
对截至2007年1月该领域的67篇科学文献进行回顾。
总结影响准捐赠者决定是否将多余胚胎用于医学研究的动机的因素。
呈现关于干细胞研究中优质人类胚胎的需求和可获得性的研究结果，讨论使用质量欠佳的胚胎进行研究的情况，以及呈现几项关于生育患者对一般胚胎捐赠用于研究尤其是干细胞研究的态度的研究结果。此外，讨论做出此类决策的困难，并提出促进准捐赠者做出理性、审慎和及时决策的建议策略。
本文的主要部分呈现了关于影响夫妻决定是否捐赠多余胚胎用于研究的因素的研究结果。研究目的、治疗阶段、胚胎质量、宗教信仰和利他主义似乎对捐赠很重要。处于治疗初期、不了解医学研究目的或拥有优质胚胎似乎会促使那些表示不想捐赠的人做出这样的决定。
