Li Bing, Evans Dewey, Faris Peter, Dean Stafford, Quan Hude
Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada.
BMC Health Serv Res. 2008 Jan 14;8:12. doi: 10.1186/1472-6963-8-12.
The performance of the Charlson and Elixhauser comorbidity measures in predicting patient outcomes have been well validated with ICD-9 data but not with ICD-10 data, especially in disease specific patient cohorts. The objective of this study was to assess the performance of these two comorbidity measures in the prediction of in-hospital and 1 year mortality among patients with congestive heart failure (CHF), diabetes, chronic renal failure (CRF), stroke and patients undergoing coronary artery bypass grafting (CABG).
A Canadian provincial hospital discharge administrative database was used to define 17 Charlson comorbidities and 30 Elixhauser comorbidities. C-statistic values were calculated to evaluate the performance of two measures. One year mortality information was obtained from the provincial Vital Statistics Department.
The absolute difference between ICD-9 and ICD-10 data in C-statistics ranged from 0 to 0.04 across five cohorts for the Charlson and Elixhauser comorbidity measures predicting in-hospital or 1 year mortality. In the models predicting in-hospital mortality using ICD-10 data, the C-statistics ranged from 0.62 (for stroke) - 0.82 (for diabetes) for Charlson measure and 0.62 (for stroke) to 0.83 (for CABG) for Elixhauser measure.
The change in coding algorithms did not influence the performance of either the Charlson or Elixhauser comorbidity measures in the prediction of outcome. Both comorbidity measures were still valid prognostic indicators in the ICD-10 data and had a similar performance in predicting short and long term mortality in the ICD-9 and ICD-10 data.
查尔森合并症测量法和埃利克斯豪泽合并症测量法在预测患者预后方面的表现已通过国际疾病分类第九版(ICD - 9)数据得到充分验证,但尚未通过国际疾病分类第十版(ICD - 10)数据验证,尤其是在特定疾病患者队列中。本研究的目的是评估这两种合并症测量法在预测充血性心力衰竭(CHF)、糖尿病、慢性肾衰竭(CRF)、中风患者以及接受冠状动脉旁路移植术(CABG)患者的住院死亡率和1年死亡率方面的表现。
使用加拿大一个省级医院出院管理数据库来定义17种查尔森合并症和30种埃利克斯豪泽合并症。计算C统计量值以评估这两种测量法的表现。从省级人口动态统计部门获取1年死亡率信息。
对于预测住院或1年死亡率的查尔森和埃利克斯豪泽合并症测量法,在五个队列中,ICD - 9和ICD - 10数据在C统计量上的绝对差值范围为0至0.04。在使用ICD - 10数据预测住院死亡率的模型中,查尔森测量法的C统计量范围为0.62(中风)至0.82(糖尿病),埃利克斯豪泽测量法的C统计量范围为0.62(中风)至0.83(冠状动脉旁路移植术)。
编码算法的改变并未影响查尔森或埃利克斯豪泽合并症测量法在预测预后方面的表现。这两种合并症测量法在ICD - 10数据中仍是有效的预后指标,并且在预测ICD - 9和ICD - 10数据中的短期和长期死亡率方面表现相似。