Vranić L, Granić P, Rajić Z
School of Dentistry, University of Zagreb.
Acta Stomatol Croat. 1991;25(2):71-6.
Amino acid pattern in total saliva was studied in 43 children with caries, aged 12-15 years, using the method of ion exchange chromatography. The results were compared to those obtained in a control group of 39 children without caries. In saliva from the children with caries, a significantly lower level of arginine (22.02 mumol/l), and a complete lack of histidine and its derivatives were observed when compared to the control group, where the concentrations of arginine and 1-methylhistidine were 28.36 and 26.34 mumol/l, respectively. The results obtained suggested that a decreased concentration of arginine, and a lack of histidine and its derivatives might imply an increased risk of caries.
采用离子交换色谱法对43名12至15岁患龋儿童的全唾液氨基酸模式进行了研究。将结果与39名无龋儿童的对照组进行了比较。与对照组相比，患龋儿童唾液中精氨酸水平显著降低（22.02μmol/L），且完全缺乏组氨酸及其衍生物，对照组中精氨酸和1-甲基组氨酸的浓度分别为28.36和26.34μmol/L。所得结果表明，精氨酸浓度降低以及组氨酸及其衍生物缺乏可能意味着患龋风险增加。
