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金属致癌作用的流行病学和实验研究:物理化学性质、动力学及活性物种

Epidemiological and experimental aspects of metal carcinogenesis: physicochemical properties, kinetics, and the active species.

作者信息

Magos L

机构信息

MRC Toxicology Unit, Carshalton, Surrey, UK.

出版信息

Environ Health Perspect. 1991 Nov;95:157-89. doi: 10.1289/ehp.9195157.

Abstract

The carcinogenic properties of selected metals and their compounds are reviewed to provide a useful reference for existing knowledge on relationships between physical and chemical forms, kinetics and carcinogenic potential and between epidemiology, bioassays, and short-term tests. Extensive consideration is given to arsenic, beryllium, cadmium, chromium, lead, and nickel. Other metals such as antimony, cobalt, copper, iron, manganese, selenium, and zinc are discussed briefly.

摘要

本文综述了特定金属及其化合物的致癌特性,为有关物理和化学形态、动力学与致癌潜力之间以及流行病学、生物测定和短期测试之间关系的现有知识提供有用参考。文中对砷、铍、镉、铬、铅和镍进行了广泛探讨。其他金属如锑、钴、铜、铁、锰、硒和锌则作了简要讨论。

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