Weber Bryan A, Roberts Beverly L, Chumbler Neale R, Mills Terry L, Algood Chester B
University of Florida, Gainesville, FL, USA.
Urol Nurs. 2007 Dec;27(6):527-33.
Radical prostatectomy results in greater persistence of urinary and sexual dysfunction (and to a minor degree, bowel dysfunction) than other forms of prostate cancer treatment. These physical side effects create bother, which is the degree of annoyance, dysfunction, or discomfort associated with treatment aftermath.
The purpose of this study was to assess the relationships between post-radical prostatectomy urinary, sexual, and bowel dysfunction, and the resultant bother to determine which of the physical dysfunctions bothers men the most.
Seventy-two men were recruited and surveyed 6 weeks after radical prostatectomy. Outcome measures included self-efficacy (Stanford Inventory of Cancer Patient Adjustment), social support (Modified Inventory of Socially Supportive Behaviors), uncertainty (Uncertainty in Illness Scale), and physical function and bother (UCLA Prostate Cancer Index).
Sexual dysfunction had the highest prevalence among treatment side effects caused by radical prostatectomy. However, it was urinary dysfunction in terms of incontinence that was the most bothersome.
Given various treatment options for prostate cancer, men who undergo radical prostatectomy initially decide that the physical dysfunction is worth the benefits of improved likelihood of survival; however, they do so without firsthand knowledge of the associated bother. Patients should be informed of the transient and unrelenting physical symptoms and associated bother that are produced after radical prostatectomy.
与其他形式的前列腺癌治疗相比，根治性前列腺切除术导致的泌尿和性功能障碍（以及程度较轻的肠道功能障碍）持续时间更长。这些身体副作用会造成困扰，即与治疗后果相关的烦恼、功能障碍或不适程度。
本研究的目的是评估根治性前列腺切除术后泌尿、性和肠道功能障碍之间的关系，以及由此产生的困扰，以确定哪种身体功能障碍对男性困扰最大。
招募了72名男性，在根治性前列腺切除术后6周进行调查。结果测量包括自我效能感（斯坦福癌症患者适应量表）、社会支持（社会支持行为修正量表）、不确定性（疾病不确定性量表）以及身体功能和困扰（加州大学洛杉矶分校前列腺癌指数）。
性功能障碍在根治性前列腺切除术引起的治疗副作用中患病率最高。然而，就失禁而言，泌尿功能障碍是最困扰人的。
鉴于前列腺癌有多种治疗选择，接受根治性前列腺切除术的男性最初认为身体功能障碍值得以提高生存可能性为代价；然而，他们这样做时并未直接了解相关的困扰。应告知患者根治性前列腺切除术后产生的短暂且持续的身体症状及相关困扰。
