Martins Carla, Siqueira Walter Luiz, Guimarães Primo Laura S S
Department of Pediatric Dentistry and Orthodontics, School of Dentistry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Pediatr Nephrol. 2008 Apr;23(4):619-24. doi: 10.1007/s00467-007-0718-5. Epub 2008 Jan 29.
We have described the oral status and salivary flow rate of 30 children and adolescents suffering from chronic renal failure (CRF) undergoing hemodialysis and compared the associated parameters with those of 30 clinically healthy subjects with no history of chronic disease. The subjects of the renal group (RG) and healthy group (HG) were paired by gender and age (7-19 years old). Anamneses and an interview consisting of questions on oral hygiene habits comprised the first step in the study, followed by whole and parotid saliva collection and intra-oral examination. No statistical significant difference was found between the RG and HG subjects in terms of the presence of gingival inflammation, dental history of caries, and enamel hypoplasia. However, statistical significant differences were found between the groups related to a sensation of dry mouth, salivary flow rate, delayed tooth eruption, dental staining by iron supplementation, presence of plaque, and dental calculus. Based on our results, we conclude that CRF children and adolescents undergoing hemodialysis present some oral manifestations related to their disease. These manifestations include a sensation of dry mouth, delayed tooth eruption, dental staining by iron supplementation, and dental calculus. A lower flow rate of whole and parotid saliva production just before hemodialysis was also observed.
我们描述了30名接受血液透析的慢性肾衰竭（CRF）儿童和青少年的口腔状况及唾液流速，并将相关参数与30名无慢性疾病史的临床健康受试者进行了比较。肾疾病组（RG）和健康组（HG）的受试者按性别和年龄（7至19岁）进行配对。研究的第一步是收集病史并进行关于口腔卫生习惯的访谈，随后进行全唾液和腮腺唾液采集以及口腔内检查。在牙龈炎症的存在、龋齿病史和釉质发育不全方面，RG组和HG组受试者之间未发现统计学上的显著差异。然而，在口干感、唾液流速、牙齿萌出延迟、补铁导致的牙齿染色、牙菌斑的存在和牙结石方面，两组之间发现了统计学上的显著差异。根据我们的结果，我们得出结论，接受血液透析的CRF儿童和青少年存在一些与其疾病相关的口腔表现。这些表现包括口干感、牙齿萌出延迟、补铁导致的牙齿染色和牙结石。在血液透析前还观察到全唾液和腮腺唾液分泌流速较低。
