餐后代谢紊乱：糖尿病与心血管事件之间缺失的环节？
Postprandial dysmetabolism: the missing link between diabetes and cardiovascular events?
作者信息
Bell David S H, O'Keefe James H, Jellinger Paul
机构信息
Southside Endocrinology, Birmingham, Alabama 35205, USA.
出版信息
Endocr Pract. 2008 Jan-Feb;14(1):112-24. doi: 10.4158/EP.14.1.112.
OBJECTIVE
To investigate the association of postprandial dysmetabolism, ie, hyperglycemia, and hyperlipidemia with myocardial disease in diabetic, glucose-intolerant, and glucose-tolerant patients.
METHODS
We performed a MEDLINE search of the English-language literature published between January 1979 and April 2007 for studies regarding postprandial dysmetabolism and heart disease.
RESULTS
Postprandial dysmetabolism is associated with increased inflammation, endothelial dysfunction, decreased fibrinolysis, plaque instability, and cardiac events.
CONCLUSION
There is a direct and proportional association between postprandial dysmetabolism and both coronary artery disease and cardiac events.
目的
研究糖尿病患者、糖耐量受损患者及糖耐量正常患者的餐后代谢紊乱（即高血糖和高脂血症）与心肌病之间的关联。
方法
我们对1979年1月至2007年4月间发表的英文文献进行了MEDLINE检索，以查找有关餐后代谢紊乱与心脏病的研究。
结果
餐后代谢紊乱与炎症增加、内皮功能障碍、纤维蛋白溶解减少、斑块不稳定及心脏事件相关。
结论
餐后代谢紊乱与冠状动脉疾病和心脏事件之间存在直接且成比例的关联。
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