Murphy F A, Whitfield S G
Bull World Health Organ. 1975;52(4-6):409-19.
Arenaviruses have unique structural characteristics; they are pleomorphic, have a mean diameter of 110-130 nm, and consist of a membranous envelope with surface projections surrounding an interior containing ribosomes and filaments. Virus particles bud from plasma membranes of infected cells and in many cases large intracytoplasmic inclusion bodies are formed. These characteristics allow generic identification, but not differentiation of individual viruses. Ultrastructural identification of virus particles and pathological processes in infected tissues of man and experimental animals is important in understanding the nature of arenaviral pathogenesis Such identification also contributes to our understanding of the mechanisms of viral shedding and transmission in reservoir host species.
沙粒病毒具有独特的结构特征；它们形态多样，平均直径为110 - 130纳米，由一个带有表面突起的膜状包膜组成，包膜围绕着一个包含核糖体和细丝的内部结构。病毒粒子从受感染细胞的质膜出芽，在许多情况下会形成大的胞质内包涵体。这些特征有助于进行属的鉴定，但无法区分个别病毒。对人和实验动物感染组织中的病毒粒子和病理过程进行超微结构鉴定，对于理解沙粒病毒发病机制的本质很重要。这种鉴定也有助于我们了解病毒在储存宿主物种中的释放和传播机制。
