Arai Satoru, Bennett Shannon N, Sumibcay Laarni, Cook Joseph A, Song Jin-Won, Hope Andrew, Parmenter Cheryl, Nerurkar Vivek R, Yates Terry L, Yanagihara Richard
John A. Burns School of Medicine, University of Hawai'i at Manoa, Honolulu, Hawai'i 96813, USA.
Am J Trop Med Hyg. 2008 Feb;78(2):348-51.
A limited search for hantaviruses in lung and liver tissues of Sorex shrews (family Soricidae, subfamily Soricinae) revealed phylogenetically distinct hantaviruses in the masked shrew (Sorex cinereus) from Minnesota and in the dusky shrew (Sorex monticolus) from New Mexico and Colorado. The discovery of these shrew-borne hantaviruses, named Ash River virus and Jemez Springs virus, respectively, challenges the long-held dogma that rodents are the sole reservoir hosts and forces a re-examination of their co-evolutionary history. Also, studies now underway are aimed at clarifying the epizootiology and pathogenicity of these new members of the genus Hantavirus.
在食虫目鼩鼱科鼩鼱亚科的肺和肝组织中对汉坦病毒进行的有限搜索发现,在明尼苏达州的隐鼩(Sorex cinereus)以及新墨西哥州和科罗拉多州的暗足鼩(Sorex monticolus)中存在系统发育上不同的汉坦病毒。这些分别名为阿什河病毒和杰梅斯泉病毒的由鼩鼱传播的汉坦病毒的发现,挑战了长期以来认为啮齿动物是唯一储存宿主的教条,并促使人们重新审视它们的共同进化历史。此外,目前正在进行的研究旨在阐明汉坦病毒属这些新成员的动物流行病学和致病性。