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待 重组,仅纳入完全测序的病毒:行动呼吁。

Pending Reorganization of to Include Only Completely Sequenced Viruses: A Call to Action.

机构信息

Integrated Research Facility at Fort Detrick, Division of Clinical Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, MD 21702, USA.

Department of Internal Medicine, University of New Mexico Health Sciences Center, Albuquerque, NM 87131, USA.

出版信息

Viruses. 2023 Feb 28;15(3):660. doi: 10.3390/v15030660.

Abstract

The official classification of newly discovered or long-known unassigned viruses by the International Committee on Taxonomy of Viruses (ICTV) requires the deposition of coding-complete or -near-complete virus genome sequences in GenBank to fulfill a requirement of the taxonomic proposal (TaxoProp) process. However, this requirement is fairly new; thus, genomic sequence information is fragmented or absent for many already-classified viruses. As a result, taxon-wide modern phylogenetic analyses are often challenging, if not impossible. This problem is particularly eminent among viruses with segmented genomes, such as bunyavirals, which were frequently classified solely based on single-segment sequence information. To solve this issue for one bunyaviral family, , we call on the community to provide additional sequence information for incompletely sequenced classified viruses by mid-June 2023. Such sequence information may be sufficient to prevent their possible declassification during the ongoing efforts to establish a coherent, consistent, and evolution-based hantavirid taxonomy.

摘要

国际病毒分类委员会(ICTV)对新发现或长期未知未分类病毒的正式分类要求将编码完整或接近完整的病毒基因组序列提交到 GenBank,以满足分类提案(TaxoProp)过程的要求。然而,这一要求相当新;因此,许多已分类的病毒的基因组序列信息是不完整的或缺失的。因此,对许多已经分类的病毒进行全分类群的现代系统发育分析往往具有挑战性,如果不是不可能的话。这个问题在具有分段基因组的病毒中尤为突出,例如 Bunyavirales,它们以前通常仅基于单一段序列信息进行分类。为了解决这个问题,我们呼吁社区在 2023 年 6 月中旬之前为未完全测序的分类病毒提供额外的序列信息。这些序列信息可能足以防止它们在正在进行的建立一致、一致和基于进化的汉坦病毒分类学的努力中被可能的重新分类。

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