Department of Chemistry, Zakir Husain College, University of Delhi, Jawaharlal Nehru Marg, New Delhi 110002, India.
Bioinorg Chem Appl. 2007;2007:51483. doi: 10.1155/2007/51483.
A series of metal complexes of Cu(II) and Ni(II) having the general composition [M(L)X(2)] with benzil bis(thiosemicarbazone) has been prepared and characterized by element chemical analysis, molar conductance, magnetic susceptibility measurements, and spectral (electronic, IR, EPR, mass) studies. The IR spectral data suggest the involvement of sulphur and azomethane nitrogen in coordination to the central metal ion. On the basis of spectral studies, an octahedral geometry has been assigned for Ni(II) complexes but a tetragonal geometry for Cu(II) complexes. The free ligand and its metal complexes have been tested in vitro against a number of microorganisms in order to assess their antimicrobial properties.
已经制备了一系列具有通式 [M(L)X(2)] 的 Cu(II)和 Ni(II)的金属配合物，其中 L 为苯甲酰双（硫代缩氨基脲），X 为卤化物。通过元素化学分析、摩尔电导率、磁化率测量和光谱（电子、IR、EPR、质谱）研究对其进行了表征。IR 光谱数据表明硫原子和氮原子参与了与中心金属离子的配位。基于光谱研究，Ni(II)配合物被赋予八面体几何构型，而 Cu(II)配合物则被赋予四方锥几何构型。为了评估它们的抗菌性能，已经在体外对游离配体及其金属配合物进行了对多种微生物的测试。
