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近平滑念珠菌和正平滑念珠菌的患病率及易感性概况：西班牙念珠菌血症人群监测结果

Prevalence and susceptibility profile of Candida metapsilosis and Candida orthopsilosis: results from population-based surveillance of candidemia in Spain.

作者信息

Gomez-Lopez A, Alastruey-Izquierdo A, Rodriguez D, Almirante B, Pahissa A, Rodriguez-Tudela J L, Cuenca-Estrella M

机构信息

Servicio de Micología, Centro Nacional de Microbiología, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain.

出版信息

Antimicrob Agents Chemother. 2008 Apr;52(4):1506-9. doi: 10.1128/AAC.01595-07. Epub 2008 Feb 19.

DOI:10.1128/AAC.01595-07
PMID:18285486
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2292570/
Abstract

We describe the prevalences and susceptibility profiles of two recently described species, Candida metapsilosis and Candida orthopsilosis, related to Candida parapsilosis in candidemia. The prevalences of these species (1.7% for C. metapsilosis and 1.4% for C. orthopsilosis) are significant. Differences observed in their susceptibility profiles could have therapeutic importance.

摘要

我们描述了两种最近发现的念珠菌属物种——近平滑念珠菌和正平滑念珠菌在念珠菌血症中的流行率及药敏谱，它们与近平滑念珠菌相关。这些物种的流行率（近平滑念珠菌为1.7%，正平滑念珠菌为1.4%）具有统计学意义。在它们的药敏谱中观察到的差异可能具有治疗重要性。

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本文引用的文献

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J Clin Microbiol. 2008 Aug;46(8):2659-64. doi: 10.1128/JCM.00803-08. Epub 2008 Jun 18.
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Paradoxical growth effect of caspofungin observed on biofilms and planktonic cells of five different Candida species.在五种不同念珠菌的生物膜和浮游细胞上观察到卡泊芬净的矛盾生长效应。
Antimicrob Agents Chemother. 2007 Sep;51(9):3081-8. doi: 10.1128/AAC.00676-07. Epub 2007 Jun 25.
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Virulence of Candida parapsilosis, Candida orthopsilosis, and Candida metapsilosis in reconstituted human tissue models.近平滑念珠菌、正平滑念珠菌和间平滑念珠菌在重组人体组织模型中的毒力。
Fungal Genet Biol. 2007 Dec;44(12):1336-41. doi: 10.1016/j.fgb.2007.02.002. Epub 2007 Feb 21.
4
Genotyping of Candida orthopsilosis clinical isolates by amplification fragment length polymorphism reveals genetic diversity among independent isolates and strain maintenance within patients.通过扩增片段长度多态性对近平滑念珠菌临床分离株进行基因分型，揭示了独立分离株之间的遗传多样性以及患者体内的菌株维持情况。
J Clin Microbiol. 2007 May;45(5):1455-62. doi: 10.1128/JCM.00243-07. Epub 2007 Feb 28.
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J Med Microbiol. 2007 Feb;56(Pt 2):190-195. doi: 10.1099/jmm.0.46838-0.
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