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本文引用的文献

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Multiplex PCR for detection of plasmid-mediated quinolone resistance qnr genes in ESBL-producing enterobacterial isolates.用于检测产超广谱β-内酰胺酶肠杆菌分离株中质粒介导喹诺酮耐药qnr基因的多重聚合酶链反应
J Antimicrob Chemother. 2007 Aug;60(2):394-7. doi: 10.1093/jac/dkm204. Epub 2007 Jun 8.
2
16S ribosomal RNA methylation: emerging resistance mechanism against aminoglycosides.16S核糖体RNA甲基化：针对氨基糖苷类抗生素新出现的耐药机制
Clin Infect Dis. 2007 Jul 1;45(1):88-94. doi: 10.1086/518605. Epub 2007 May 21.
3
New plasmid-mediated fluoroquinolone efflux pump, QepA, found in an Escherichia coli clinical isolate.在一株大肠杆菌临床分离株中发现新型质粒介导的氟喹诺酮外排泵QepA。
Antimicrob Agents Chemother. 2007 Sep;51(9):3354-60. doi: 10.1128/AAC.00339-07. Epub 2007 Jun 4.
4
Transferable resistance to aminoglycosides by methylation of G1405 in 16S rRNA and to hydrophilic fluoroquinolones by QepA-mediated efflux in Escherichia coli.大肠杆菌中16S rRNA的G1405甲基化介导对氨基糖苷类的可转移耐药性以及QepA介导的外排作用导致对亲水性氟喹诺酮类的可转移耐药性。
Antimicrob Agents Chemother. 2007 Jul;51(7):2464-9. doi: 10.1128/AAC.00143-07. Epub 2007 Apr 30.
5
First detection of the plasmid-mediated quinolone resistance determinant qnrA in Enterobacteriaceae clinical isolates in Japan.在日本肠杆菌科临床分离株中首次检测到质粒介导的喹诺酮耐药决定簇qnrA。
Int J Antimicrob Agents. 2007 Jun;29(6):738-9. doi: 10.1016/j.ijantimicag.2007.01.010. Epub 2007 Mar 19.
6
Prevalence of plasmid-mediated quinolone resistance determinants QnrA, QnrB, and QnrS among clinical isolates of Enterobacter cloacae in a Taiwanese hospital.台湾一家医院阴沟肠杆菌临床分离株中质粒介导的喹诺酮耐药决定子QnrA、QnrB和QnrS的流行情况。
Antimicrob Agents Chemother. 2007 Apr;51(4):1223-7. doi: 10.1128/AAC.01195-06. Epub 2007 Jan 22.
7
Detection of plasmid-mediated quinolone resistance associated with qnrA in an Escherichia coli clinical isolate producing CTX-M-9 beta-lactamase in Japan.在日本一株产CTX-M-9β-内酰胺酶的大肠埃希菌临床分离株中检测到与qnrA相关的质粒介导喹诺酮耐药性
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8
The worldwide emergence of plasmid-mediated quinolone resistance.质粒介导的喹诺酮耐药性在全球范围内的出现。
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9
qnr prevalence in ceftazidime-resistant Enterobacteriaceae isolates from the United States.美国耐头孢他啶肠杆菌科分离株中qnr的流行情况。
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10
qnrB, another plasmid-mediated gene for quinolone resistance.qnrB，另一种质粒介导的喹诺酮耐药基因。
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日本临床分离大肠埃希菌中的质粒介导qepA基因

Plasmid-mediated qepA gene among Escherichia coli clinical isolates from Japan.

作者信息

Yamane Kunikazu, Wachino Jun-ichi, Suzuki Satowa, Arakawa Yoshichika

机构信息

Department of Bacterial Pathogenesis and Infection Control, National Institute of Infectious Diseases, 4-7-1 Gakuen, Musashi-Murayama, Tokyo 208-0011, Japan.

出版信息

Antimicrob Agents Chemother. 2008 Apr;52(4):1564-6. doi: 10.1128/AAC.01137-07. Epub 2008 Feb 19.

DOI:10.1128/AAC.01137-07
PMID:18285488
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2292543/
Abstract

Seven hundred fifty-one Escherichia coli clinical isolates collected from 140 Japanese hospitals between 2002 and 2006 were screened for the qepA and qnr genes. Two E. coli isolates (0.3%) harbored qepA, but no qnr was identified. The results suggested a low prevalence of E. coli harboring qepA or qnr in Japan.

摘要

2002年至2006年间，从140家日本医院收集了751株大肠杆菌临床分离株，对其进行qepA和qnr基因筛查。有2株大肠杆菌分离株（0.3%）携带qepA，但未鉴定出qnr。结果表明，在日本携带qepA或qnr的大肠杆菌流行率较低。