白细胞介素-1和肿瘤坏死因子在脂多糖诱导的低血糖中的作用。
Roles of interleukin-1 and tumor necrosis factor in lipopolysaccharide-induced hypoglycemia.
作者信息
Vogel S N, Henricson B E, Neta R
机构信息
Department of Microbiology, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814.
出版信息
Infect Immun. 1991 Jul;59(7):2494-8. doi: 10.1128/iai.59.7.2494-2498.1991.
Abstract
In this study, hypoglycemia induced by injection of lipopolysaccharide (LPS) or the recombinant cytokine interleukin-1 alpha or tumor necrosis factor alpha (administered alone or in combination) was compared. LPS-induced hypoglycemia was reversed significantly by recombinant interleukin-1 receptor antagonist.
摘要
在本研究中，比较了注射脂多糖（LPS）或重组细胞因子白细胞介素-1α或肿瘤坏死因子α（单独或联合给药）诱导的低血糖。重组白细胞介素-1受体拮抗剂可显著逆转LPS诱导的低血糖。
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