Wong See C, Ooi Mong H, Abdullah Abdul R, Wong See Y, Krishnan Shekhar, Tio Phaik H, Pek Peng C, Lai Boon F, Mohan Anand, Muhi Jamail, Kiyu Andrew, Arif Mohamad T, Cardosa Mary J
Sibu Hospital, Sibu, Sarawak, Malaysia.
Trop Med Int Health. 2008 Jan;13(1):52-5. doi: 10.1111/j.1365-3156.2007.01967.x.
Japanese encephalitis virus (JEV) is an important encephalitis virus in Asia, but there are few data on Malaysia. A hospital-based surveillance system for Japanese encephalitis (JE) has been in operation in Sarawak, Malaysia, for the last 10 years. JEV is endemic in Sarawak, with cases occurring throughout the year and a seasonal peak in the last quarter (one-way anova, P < 0.0001). Ninety-two per cent of 133 cases were children aged 12 years or younger; the introduction of JE vaccination in July 2001 reduced the number of JE cases (84 in the four seasons prior to vs. 49 in the six seasons after, McNemar's test, P = 0.0001). After implementation of the programme, the mean age of infected children increased from 6.3 to 8.0 years (Student's t-test, P = 0.0037), suggesting the need for a catch-up programme.
日本脑炎病毒（JEV）是亚洲一种重要的脑炎病毒，但关于马来西亚的相关数据却很少。在过去十年里，马来西亚砂拉越州一直运行着一个基于医院的日本脑炎（JE）监测系统。JEV在砂拉越州呈地方流行性，全年都有病例发生，且在最后一个季度出现季节性高峰（单因素方差分析，P < 0.0001）。133例病例中，92%为12岁及以下儿童；2001年7月引入JE疫苗后，JE病例数量有所减少（之前四个季节有84例，之后六个季节有49例，McNemar检验，P = 0.0001）。该计划实施后感染儿童的平均年龄从6.3岁增至8.0岁（Student's t检验，P = 0.0037），这表明需要开展补种计划。
