Serum alpha-1-antitriypsin levels in patients with pseudoexfolative syndrome.

PURPOSE

To evaluate the levels of serum alpha 1-antitrypsin in patients with pseudoexfoliation syndrome (PEX) and healthy control subjects without PEX.

MATERIAL AND METHODS

Forty-four patient with PEX and 40 healthy control subjects (84 subjects total) were enrolled into the study. Serum ATT levels were measured using nephelometry.

RESULTS

The mean serum AAT concentration in PEX group was significantly higher than in the controls (p=0.0001).

CONCLUSION

Serum AAT levels were found to be increased in patients with PEX. Increased serum AAT levels in PEX may explain the role of inflammation in this group of patients.