Huber-Spitzy V, Baumgartner I, Böhler-Sommeregger K, Grabner G
2nd Department of Ophthalmology, University of Vienna, Austria.
Graefes Arch Clin Exp Ophthalmol. 1991;229(3):224-7. doi: 10.1007/BF00167872.
Over the last few years the number of patients with chronic bilateral blepharitis has increased dramatically. From January 1985 until the end of 1989, a total of 407 patients with this diagnosis underwent ophthalmological and dermatological investigations at our out-patient clinic. Keratoconjunctivitis sicca (KCS) in conjunction with blepharitis occurred in 14.5% of the patient population who also suffered from acne rosacea. A comparison of the spectrum of microorganisms that have previously been isolated from affected sites with data obtained in the present study revealed that the range of microorganisms associated with this chronic localized inflammation has apparently shifted in recent years. The prevalence of Staphylococcus aureus, which was considerable in the pre-antibiotic era, has markedly decreased, although a distinct entity of staphylococcal blepharitis seems to remain, either alone or in combination with seborrheic blepharitis (62.8% of our patients). The clinical picture, microbiological findings and therapy for this condition are presented.
在过去几年中，慢性双侧睑缘炎患者的数量急剧增加。从1985年1月到1989年底，共有407例诊断为此病的患者在我们的门诊接受了眼科和皮肤科检查。干燥性角结膜炎（KCS）合并睑缘炎发生在14.5%同时患有酒渣鼻的患者中。将先前从患病部位分离出的微生物谱与本研究获得的数据进行比较后发现，与这种慢性局部炎症相关的微生物范围近年来显然已经发生了变化。在抗生素时代之前相当常见的金黄色葡萄球菌的患病率已显著下降，尽管金黄色葡萄球菌性睑缘炎这一独特类型似乎仍然存在，无论是单独存在还是与脂溢性睑缘炎合并存在（在我们的患者中占62.8%）。本文介绍了这种疾病的临床表现、微生物学检查结果及治疗方法。
