Liu Ling, Liu Shuchun, Jiang Lihua, Chen Xulin, Guo Liangdong, Che Yongsheng
Key Laboratory of Systematic Mycology and Lichenology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100080, People's Republic of China.
Org Lett. 2008 Apr 3;10(7):1397-400. doi: 10.1021/ol800136t. Epub 2008 Mar 4.
Chloropupukeananin (1), the first pupukeanane chloride with highly functionalized tricyclo-[4.3.1.03,7]-decane skeleton and its possible biosynthetic precursors iso-A82775C (2) and pestheic acid (3), have been isolated from the plant endophyte Pestalotiopsis fici. The structure of 1 was determined by NMR spectroscopy and X-ray crystallography. Biogenetically, 1 could be derived from the Diels-Alder adduct of 2 and 3.
氯普库安宁（1）是首个具有高度官能化三环[4.3.1.03,7]-癸烷骨架的普库安烷氯化物，及其可能的生物合成前体异A82775C（2）和佩斯特酸（3），已从植物内生真菌拟盘多毛孢中分离得到。1的结构通过核磁共振光谱和X射线晶体学确定。从生源论角度来看，1可能源自2和3的狄尔斯-阿尔德加成物。
