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肾移植术后并发症：聚焦BK病毒肾病及现有的诊断工具的文献

Complications post renal transplantation: literature focus on BK virus nephropathy and diagnostic tools actually available.

作者信息

Mischitelli Monica, Bellizzi Anna, Anzivino Elena, Fioriti Daniela, Boldorini Renzo, Miglio Umberto, Chiarini Fernanda, Di Monaco Franco, Pietropaolo Valeria

机构信息

Department of Public Health Sciences, La Sapienza University, Rome, Italy.

出版信息

Virol J. 2008 Mar 3;5:38. doi: 10.1186/1743-422X-5-38.

DOI:10.1186/1743-422X-5-38
PMID:18315864
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2268664/
Abstract

Clinical diagnosis of kidney transplants related illnesses is not a simple task. Several studies were conducted to define diseases and complications after renal transplantation, but there are no comprehensive guidelines about diagnostic tools for their prevention and detection. The Authors of this review looked for the medical literature and pertinent publications in particular to understand the role of Human Polyomavirus BK (BKV) in renal failure and to recognize analytical techniques for BK virus associated nephropathy (BKVAN) detection.

摘要

肾脏移植相关疾病的临床诊断并非易事。已经开展了多项研究来界定肾移植后的疾病和并发症，但对于其预防和检测的诊断工具尚无全面的指导方针。这篇综述的作者查阅了医学文献及相关出版物，特别是为了了解人多瘤病毒BK（BKV）在肾衰竭中的作用，并认识检测BK病毒相关性肾病（BKVAN）的分析技术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/489e/2268664/ab74ba2e671b/1743-422X-5-38-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/489e/2268664/aaa7949d937d/1743-422X-5-38-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/489e/2268664/ab74ba2e671b/1743-422X-5-38-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/489e/2268664/aaa7949d937d/1743-422X-5-38-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/489e/2268664/ab74ba2e671b/1743-422X-5-38-2.jpg

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本文引用的文献

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Update in nephrology.肾脏病学进展
Ann Intern Med. 2008 Jan 1;148(1):49-54. doi: 10.7326/0003-4819-148-1-200801010-00007.
2
The influence of organ acceptance criteria on long-term graft survival: outcomes of a kidney transplant program.器官接受标准对移植肾长期存活的影响：一项肾移植项目的结果
Am J Surg. 2008 Feb;195(2):149-52. doi: 10.1016/j.amjsurg.2007.11.003.
3
[Kidney transplantation: indications, results, limitations, and perspectives].[肾移植：适应证、结果、局限性及展望]
热休克蛋白90α是肾移植术后急性排斥反应的潜在血清生物标志物。
PLoS One. 2016 Sep 15;11(9):e0162942. doi: 10.1371/journal.pone.0162942. eCollection 2016.
4
Frequency of Polyomavirus BK Infection in Kidney Transplant Patients Suspected to Nephropathy.疑似肾病的肾移植患者中多瘤病毒BK感染的频率
Int J Organ Transplant Med. 2015;6(2):77-84.
5
Prospective, comprehensive, and effective viral monitoring in Cuban children undergoing solid organ transplantation.对古巴接受实体器官移植的儿童进行前瞻性、全面且有效的病毒监测。
Springerplus. 2014 May 16;3:247. doi: 10.1186/2193-1801-3-247. eCollection 2014.
6
Early monitoring of the human polyomavirus BK replication and sequencing analysis in a cohort of adult kidney transplant patients treated with basiliximab.在接受巴利昔单抗治疗的成年肾移植患者队列中，对人类多瘤病毒 BK 的早期监测和测序分析。
Virol J. 2011 Aug 17;8:407. doi: 10.1186/1743-422X-8-407.
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Ochsner J. 2010 Winter;10(4):245-9.
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Post-transplant infections: An ounce of prevention.移植后感染：预防为主。
Indian J Nephrol. 2010 Oct;20(4):171-8. doi: 10.4103/0971-4065.73431.
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High-throughput cell-based screen for chemicals that inhibit infection by simian virus 40 and human polyomaviruses.针对抑制猿猴病毒40和人类多瘤病毒感染的化学物质进行的基于细胞的高通量筛选。
J Virol. 2009 Jun;83(11):5630-9. doi: 10.1128/JVI.00203-09. Epub 2009 Mar 18.
Presse Med. 2007 Dec;36(12 Pt 2):1829-34. doi: 10.1016/j.lpm.2007.04.037. Epub 2007 Oct 24.
4
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