Huang Chang-Bing, Zhou Yifeng, Lu Zhong-Lin
Vision Research Laboratory, School of Life Sciences, University of Science and Technology of China, Hefei, Anhui 230027, China.
Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):4068-73. doi: 10.1073/pnas.0800824105. Epub 2008 Mar 3.
Recent studies have demonstrated that training adult amblyopes in simple visual tasks leads to significant improvements of their spatial vision. One critical question is: How much can training with one particular stimulus and task generalize to other stimuli and tasks? In this study, we estimated the bandwidth of perceptual learning in teenage and adult observers with anisometropic amblyopia and compared it to that of normal observers. We measured and compared contrast sensitivity functions-i.e., sensitivity to sine-wave gratings of various spatial frequencies-before and after training at a single spatial frequency in teenagers and adults with and without amblyopia. We found that the bandwidth of perceptual learning in the amblyopic visual system is much broader than that of the normal visual system. The broader bandwidth, suggesting more plasticity and wider generalization in the amblyopic visual system, provides a strong empirical and theoretical basis for perceptual learning as a potential treatment for amblyopia.
最近的研究表明，训练成年弱视患者完成简单的视觉任务能显著改善他们的空间视觉。一个关键问题是：使用一种特定刺激和任务进行训练能在多大程度上推广到其他刺激和任务？在本研究中，我们估计了患有屈光参差性弱视的青少年和成年观察者的知觉学习带宽，并将其与正常观察者的进行比较。我们测量并比较了弱视和非弱视青少年及成年人在单一空间频率训练前后的对比敏感度函数，即对各种空间频率正弦波光栅的敏感度。我们发现，弱视视觉系统中的知觉学习带宽比正常视觉系统的宽得多。更宽的带宽表明弱视视觉系统具有更大的可塑性和更广泛的推广性，为将知觉学习作为弱视的一种潜在治疗方法提供了强有力的实证和理论基础。
