Ross Stuart A, McKenna Anne, Mozejko Sheila, Fick Gordon H
Faculty of medicine, University of Calgary, # 238-4411 16th Ave NW, Calgary, AB, Canada.
Exp Diabetes Res. 2007;2007:76271. doi: 10.1155/2007/76271.
High prevalence rates of type 2 diabetes are being observed in native Canadian communities. It is believed that native populations have a higher prevalence rate of vascular complications than nonnatives. The Southern Alberta Study of Diabetic Retinopathy (DR) examined the prevalence and incidence of DR and associated metabolic abnormalities in native and nonnative subjects. Prevalence rates of DR in type 2 diabetic native and nonnative subjects were identical, with a prevalence rate of 40%. Native subjects with retinopathy, however, tended to have more advanced changes of retinopathy compared to the nonnative subjects. Key factors such as A1c, blood pressure, duration of diabetes, and lipid values were not significantly different between the two cohorts. These data indicate that ethnicity does play a role in the development and severity of DR but potential risk factors that may affect the development of retinopathy are not significantly different between native and nonnative groups.
在加拿大原住民社区中，2型糖尿病的患病率很高。据信，原住民人群血管并发症的患病率高于非原住民。艾伯塔省南部糖尿病视网膜病变（DR）研究调查了原住民和非原住民受试者中DR的患病率、发病率以及相关代谢异常情况。2型糖尿病原住民和非原住民受试者中DR的患病率相同，均为40%。然而，与非原住民受试者相比，患有视网膜病变的原住民受试者往往有更严重的视网膜病变变化。两个队列之间的糖化血红蛋白（A1c）、血压、糖尿病病程和血脂值等关键因素没有显著差异。这些数据表明，种族确实在DR的发生和严重程度中起作用，但可能影响视网膜病变发生的潜在危险因素在原住民和非原住民群体之间没有显著差异。
