Vogt K, Rodloff A C, Hahn H
Institut für Medizinische Mikrobiologie, Freie Universität Berlin.
Infection. 1991 May-Jun;19(3):138-9. doi: 10.1007/BF01643232.
The combined activities of trospectomycin, a spectinomycin analogue, and colloidal bismuth subcitrate against Helicobacter pylori were investigated, the agar dilution method being employed. Forty-seven strains of H. pylori were examined. An additive effect was observed in 89%, and a synergistic interaction in 11% of the isolates. There was no antagonism observed. The MIC50 of trospectomycin against H. pylori was 2 mg/l; the MIC ranged from 0.5 to 4 mg/l.
研究了大观霉素类似物曲古霉素与枸橼酸铋胶体联合对幽门螺杆菌的活性，采用琼脂稀释法。检测了47株幽门螺杆菌。在89%的分离株中观察到相加作用，11%的分离株中观察到协同相互作用。未观察到拮抗作用。曲古霉素对幽门螺杆菌的MIC50为2mg/L；MIC范围为0.5至4mg/L。
