Dumont-Wallon Gwenaelle, Dréno Brigitte
Clinique dermatologique, CHU Hôtel-Dieu, F-44000, Nantes, France.
Presse Med. 2008 Apr;37(4 Pt 1):585-91. doi: 10.1016/j.lpm.2007.07.014. Epub 2008 Mar 7.
Our aim was to examine the specific clinical and therapeutic characteristics of acne in women seen in our practice.
This retrospective observational study included all women older than 25 years seen in our practice between 1 January 2001 and 31 December 2003.
The mean age of the 79 women included in the study was 31.8 years; 67% reported a family history of acne; 79% reported at least one acne-promoting factor, 62% regular cosmetic use. Acne began at a mean age of 16.6 years, and only 13% had lesions before menarche. Before referral, they had received an average of 2.3+/-1.6 systemic treatments and 43% had already been treated by isotretinoin. Over an average follow-up period of 11 months, 83% of those for whom we prescribed isotretinoin had complete remissions, and 17% a partial response.
Acne in women seems to be a persistent form of juvenile acne. Most of the cases we saw were inflammatory acne, with extrafacial lesions in one third of cases. The high frequency of familial history and severe seborrhea suggest a genetic factor. We also noticed the influence of the premenstrual period, stress, sun exposure and cosmetic use. Isotretinoin treatment produced the best therapeutic response.
我们的目的是研究在我们诊所就诊的女性痤疮患者的具体临床和治疗特征。
这项回顾性观察研究纳入了2001年1月1日至2003年12月31日期间在我们诊所就诊的所有25岁以上女性。
该研究纳入的79名女性的平均年龄为31.8岁；67%有痤疮家族史；79%报告至少有一个促痤疮因素，62%经常使用化妆品。痤疮发病的平均年龄为16.6岁，只有13%在初潮前有皮损。转诊前，她们平均接受了2.3±1.6次系统治疗，43%已经接受过异维A酸治疗。在平均11个月的随访期内，我们为其开具异维A酸处方的患者中，83%完全缓解，17%部分缓解。
女性痤疮似乎是青少年痤疮的一种持续形式。我们所见的大多数病例为炎性痤疮，三分之一的病例有面部以外的皮损。家族史和重度皮脂溢出的高频率提示存在遗传因素。我们还注意到月经前期、压力、日晒和化妆品使用的影响。异维A酸治疗产生了最佳治疗反应。
