自动检测未成熟血小板以用于儿科患者血小板输注指征的决策制定。
Automatic detection of immature platelets for decision making regarding platelet transfusion indications for pediatric patients.
作者信息
Saigo Katsuyasu, Sakota Yasuyuki, Masuda Yukako, Matsunaga Kyoko, Takenokuchi Mariko, Nishimura Kunihiro, Sugimoto Takeshi, Sakurai Kosuke, Hashimoto Makoto, Yanai Tomoko, Hayakawa Akira, Takeshima Yasuhiro, Nomura Tsutomu, Kubota Yoshitsugu, Kumagai Shunichi
机构信息
Blood Transfusion Division, Kobe University Hospital, Chuo-ku, Kobe 650-0017, Japan.
出版信息
Transfus Apher Sci. 2008 Apr;38(2):127-32. doi: 10.1016/j.transci.2008.01.003. Epub 2008 Mar 10.
Immature or reticulated platelets are known as a clinical marker of thrombopoiesis. Recently, an automatic method was established to detect reticulated platelets as immature platelet fraction (IPF) by means of hematology analyzer XE-2100. We assessed the effects of IPF detection after chemotherapy for various pediatric malignant disorders of 16 patients. Our results indicate that IPF should be considered a useful marker of imminent platelet recovery so that unnecessary platelet transfusion can be avoided.
未成熟或网状血小板是已知的血小板生成的临床标志物。最近，通过血液分析仪XE - 2100建立了一种自动方法来检测网状血小板，将其作为未成熟血小板分数（IPF）。我们评估了16例各种小儿恶性疾病化疗后IPF检测的效果。我们的结果表明，IPF应被视为即将发生血小板恢复的有用标志物，从而可以避免不必要的血小板输注。
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