van Urk H, Gussenhoven W J, Gerritsen G P, Pieterman H, The S H, van Egmond F, Lancée C T, Bom N
University Hospital Dijkzigt, Erasmus University Rotterdam, Department of Vascular Surgery, The Netherlands.
Int J Card Imaging. 1991;6(3-4):157-64. doi: 10.1007/BF01797848.
Clinical application of intravascular ultrasound to assess arterial atherosclerotic disease was introduced in humans after extensive in vitro and in vivo animal studies. Real-time images, obtained with a 30 MHz element mounted on a 5 F catheter, consistently confirmed angiographic images, up till now considered to be the gold standard. In addition to these data, ultrasonic cross-sectional imaging provided information on the composition of atheroselectic lesions and the size and shape of the lumen. Based on the experimentally derived criteria for tissue characterization, a better insight into arterial morphology could be obtained, allowing improved planning of interventional or reconstructional procedures. Moreover intravascular ultrasound has proved valuable as a post-interventional procedure to monitor and assess the quality of interventional results. The ultrasound images are clearly superior to angiographic studies, albeit the ultrasonic information is an adjunct to angiography and, as yet, not a substitute. We present our initial experience with intravascular ultrasound obtained in patients with substantial peripheral arterial disease.
在广泛的体外和体内动物研究之后，血管内超声在评估动脉粥样硬化疾病方面的临床应用被引入人体。通过安装在5F导管上的30MHz探头获得的实时图像，始终能证实血管造影图像，而血管造影图像至今一直被视为金标准。除了这些数据外，超声横断面成像还提供了关于动脉粥样硬化病变的组成以及管腔大小和形状的信息。基于实验得出的组织特征标准，可以更好地了解动脉形态，从而改进介入或重建手术的规划。此外，血管内超声已被证明作为一种介入后程序，在监测和评估介入结果质量方面具有价值。尽管超声信息是血管造影的辅助手段，目前还不能替代血管造影，但超声图像明显优于血管造影研究。我们展示了在患有严重外周动脉疾病的患者中获得的血管内超声的初步经验。
