Rotsch T D, Spanton M, Cugier P, Plasz A C
Analytical Research Department, Abbott Laboratories, North Chicago, Illinois 60064.
Pharm Res. 1991 Aug;8(8):989-91. doi: 10.1023/a:1015844705331.
Microgram levels of clarithromycin residues on various surfaces are quantitated. After cleaning, any residual clarithromycin remaining is removed from the surface by a wet swab-dry swab technique. High-performance liquid chromatography with electrochemical detection is used for quantitation of the resulting solutions. Recoveries ranged from 93 to 118%.
对各种表面上微克级别的克拉霉素残留进行定量。清洁后，通过湿拭子-干拭子技术从表面去除残留的克拉霉素。采用带电化学检测的高效液相色谱法对所得溶液进行定量。回收率在93%至118%之间。
