Klugkist M, Sedemund-Adib B, Schmidtke C, Schmucker P, Sievers H H, Hüppe M
Klinik für Anästhesiologie, Universität zu Lübeck, Ratzeburger Allee 160, 23558 Lübeck.
Anaesthesist. 2008 May;57(5):464-74. doi: 10.1007/s00101-008-1356-4.
Since 2001 the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU), a method for the diagnosis of delirium, has been available for the Anglo American area which can also be applied to mechanically ventilated patients. This study was conducted to answer the following questions: 1. Can a German version of the CAM-ICU be applied to patients after cardiac surgery? 2. What is the prevalence rate of postoperative delirium after cardiac surgery diagnosed by the CAM-ICU? 3. Do patients with and without the diagnosis delirium differ in the clinical variables usually associated with this disorder in cardiac surgery?
A total of 194 patients undergoing cardiac surgery served as the analysis sample (85.5% of the total group). The CAM-ICU was carried out every day for 5 days after the operation. Sociodemographic and clinical variables were collected to examine the validity of CAM-ICU. Postoperative complaints were assessed by the Anaesthesiological Questionnaire for Patients (ANP).
Postoperatively, the CAM-ICU could be applied to almost all patients without any problems. The prevalence rate of delirium was 28.4% and 85.5% of the delirium diagnosed was a hypoactive subtype when diagnosed for the first time. Patients with delirium diagnosed by CAM-ICU were older (p<0.001), had a lower educational level (p<0.05), longer anaesthesia time and operation time (p<0.05), a longer postoperative ICU stay (p<0.001), were mechanically ventilated for a longer time postoperatively (p<0.001), more often reintubated (p<0.01) and had higher leucocytes postoperatively (p<0.10). More patients with delirium had the lowest postoperatively measured oxygen saturation below 95% (p<0.01).
The CAM-ICU is an economic method for the assessment of delirium which can easily be learned. It can be applied to patients after cardiac surgery without any problems.
自2001年以来,用于诊断谵妄的重症监护病房意识模糊评估法(CAM-ICU)已在英美地区可用,该方法也可应用于机械通气患者。本研究旨在回答以下问题:1. 德语版的CAM-ICU能否应用于心脏手术后的患者?2. 通过CAM-ICU诊断的心脏手术后谵妄的患病率是多少?3. 诊断为谵妄和未诊断为谵妄的患者在心脏手术中通常与该疾病相关的临床变量上是否存在差异?
共有194例接受心脏手术的患者作为分析样本(占总组的85.5%)。术后连续5天每天进行CAM-ICU评估。收集社会人口统计学和临床变量以检验CAM-ICU的有效性。术后并发症通过患者麻醉学调查问卷(ANP)进行评估。
术后,CAM-ICU几乎可以毫无问题地应用于所有患者。谵妄的患病率为28.4%,首次诊断时85.5%的谵妄为活动减退型。通过CAM-ICU诊断为谵妄的患者年龄较大(p<0.001),教育水平较低(p<0.05),麻醉时间和手术时间较长(p<0.05),术后重症监护病房停留时间较长(p<0.001),术后机械通气时间较长(p<0.001),再次插管的频率更高(p<0.01),术后白细胞计数更高(p<0.10)。更多谵妄患者术后测得的最低血氧饱和度低于95%(p<0.01)。
CAM-ICU是一种经济的谵妄评估方法,易于掌握。它可以毫无问题地应用于心脏手术后的患者。