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关于氮化硅作为用于矫形外科植入物结构陶瓷的可能性。第一部分:加工、微观结构、力学性能、细胞毒性。

On the possibility of silicon nitride as a ceramic for structural orthopaedic implants. Part I: processing, microstructure, mechanical properties, cytotoxicity.

作者信息

Mazzocchi Mauro, Bellosi Alida

机构信息

Institute for Sciences and Technology for Ceramics, National Research Council, Via Granarolo, n.64, Faenza, Ravenna 48018, Italy.

出版信息

J Mater Sci Mater Med. 2008 Aug;19(8):2881-7. doi: 10.1007/s10856-008-3417-2. Epub 2008 Mar 18.

Abstract

Notwithstanding the good combination of mechanical and tribological properties, the suitability of silicon nitride for application as prosthesis in bone reconstruction or in articular joints replacements is still controversial. This study aims to design and produce three different silicon nitride-based ceramics and to test the materials. In this Part I the microstructure and mechanical properties evidence outstanding characteristics and the cytotoxicity studies confirm that all the materials are extremely inert and biocompatible. In Part II, the wear performance and the wettability and chemical stability against different aqueous media and physiological solutions are investigated and discussed.

摘要

尽管氮化硅具有良好的机械性能和摩擦学性能,但它在骨重建或关节置换假体应用中的适用性仍存在争议。本研究旨在设计和制备三种不同的氮化硅基陶瓷并对材料进行测试。在第一部分中,微观结构和机械性能显示出优异的特性,细胞毒性研究证实所有材料都具有极高的惰性和生物相容性。在第二部分中,将对磨损性能、润湿性以及在不同水性介质和生理溶液中的化学稳定性进行研究和讨论。

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