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氮化硅陶瓷:结构、合成、性能及生物医学应用

Silicon Nitride Ceramics: Structure, Synthesis, Properties, and Biomedical Applications.

作者信息

Heimann Robert B

机构信息

Am Stadtpark 2A, D-02826 Görlitz, Germany.

出版信息

Materials (Basel). 2023 Jul 21;16(14):5142. doi: 10.3390/ma16145142.

DOI:10.3390/ma16145142
PMID:37512416
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10383158/
Abstract

Silicon nitride ceramics excel by superior mechanical, thermal, and chemical properties that render the material suitable for applications in several technologically challenging fields. In addition to high temperature, high stress applications have been implemented in aerospace gas turbines and internal combustion engines as well as in tools for metal manufacturing, forming, and machining. During the past few decades, extensive research has been performed to make silicon nitride suitable for use in a variety of biomedical applications. This contribution discusses the structure-property-application relations of silicon nitride. A comparison with traditional oxide-based ceramics confirms that the advantageous mechanical and biomedical properties of silicon nitride are based on a high proportion of covalent bonds. The present biomedical applications are reviewed here, which include intervertebral spacers, orthopedic and dental implants, antibacterial and antiviral applications, and photonic parts for medical diagnostics.

摘要

氮化硅陶瓷因其卓越的机械、热学和化学性能而表现出色,这些性能使该材料适用于多个技术挑战性领域的应用。除了高温应用外,高应力应用已在航空航天燃气轮机、内燃机以及金属制造、成型和加工工具中得以实现。在过去几十年里,人们进行了广泛的研究,以使氮化硅适用于各种生物医学应用。本文论述了氮化硅的结构-性能-应用关系。与传统氧化物基陶瓷的比较证实,氮化硅有利的机械性能和生物医学性能基于高比例的共价键。本文对目前的生物医学应用进行了综述,包括椎间间隔器、骨科和牙科植入物、抗菌和抗病毒应用以及用于医学诊断的光子部件。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e72/10383158/553cb183b502/materials-16-05142-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e72/10383158/eb37d1843d08/materials-16-05142-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e72/10383158/0f771f7849b2/materials-16-05142-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e72/10383158/0bd30930588e/materials-16-05142-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e72/10383158/9380d6702fb1/materials-16-05142-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e72/10383158/553cb183b502/materials-16-05142-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e72/10383158/eb37d1843d08/materials-16-05142-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e72/10383158/0f771f7849b2/materials-16-05142-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e72/10383158/0bd30930588e/materials-16-05142-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e72/10383158/9380d6702fb1/materials-16-05142-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5e72/10383158/553cb183b502/materials-16-05142-g005.jpg

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Silicon nitride enhances osteoprogenitor cell growth and differentiation via increased surface energy and formation of amide and nanocrystalline HA for craniofacial reconstruction.氮化硅通过增加表面能以及形成酰胺和纳米晶羟基磷灰石促进骨祖细胞生长和分化,用于颅面重建。
Med Devices Sens. 2019 Apr;2(2). doi: 10.1002/mds3.10032. Epub 2019 May 6.
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Mechanisms of instantaneous inactivation of SARS-CoV-2 by silicon nitride bioceramic.
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Rev Cient Odontol (Lima). 2024 Mar 30;12(1):e188. doi: 10.21142/2523-2754-1201-2024-188. eCollection 2024 Jan-Mar.
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Atomistic Construction of Silicon Nitride Ceramic Fiber Molecular Model and Investigation of Its Mechanical Properties Based on Molecular Dynamics Simulations.基于分子动力学模拟的氮化硅陶瓷纤维分子模型的原子构建及其力学性能研究
Materials (Basel). 2023 Sep 5;16(18):6082. doi: 10.3390/ma16186082.
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Mater Today Bio. 2021 Sep;12:100144. doi: 10.1016/j.mtbio.2021.100144. Epub 2021 Oct 1.
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