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主动脉缩窄的速度编码电影磁共振成像:血流动力学事件的功能评估

Velocity-encoded cine MR imaging in aortic coarctation: functional assessment of hemodynamic events.

作者信息

Hom Jeffrey J, Ordovas Karen, Reddy Gautham P

机构信息

Department of Radiology, Thoracic Imaging Section, University of California, San Francisco, Box 0628, L-325, 505 Parnassus Ave, San Francisco, CA 94143-0628, USA.

出版信息

Radiographics. 2008 Mar-Apr;28(2):407-16. doi: 10.1148/rg.282075705.

Abstract

Velocity-encoded cine magnetic resonance (MR) imaging is becoming the modality of choice for the clinical evaluation of aortic coarctation, a congenital narrowing of the thoracic aorta, in which a functional assessment of hemodynamic obstruction is as important as anatomic delineation. A flow-sensitive phase-contrast technique, velocity-encoded cine MR imaging is based on the principle that moving protons change phase in proportion to their velocity. Because it enables precise hemodynamic characterization, the technique is especially useful for evaluating the severity of aortic coarctation. By enabling a qualitative assessment of the presence and direction of collateral circulation, velocity-encoded cine MR imaging provides information about the presence and severity of obstruction. It also allows accurate quantitation of key hemodynamic parameters such as flow velocity, flow volume, and pressure gradients across the coarctation-functional information that is clinically useful for both preoperative planning and postinterventional monitoring. The results of recent experience indicate that velocity-encoded cine MR imaging also may be applicable for the detection of recurrent stenosis after stent placement or angioplasty.

摘要

速度编码电影磁共振(MR)成像正成为临床上评估主动脉缩窄的首选方式,主动脉缩窄是一种胸主动脉的先天性狭窄,其中血流动力学梗阻的功能评估与解剖学描绘同样重要。速度编码电影MR成像是一种血流敏感的相位对比技术,基于移动质子根据其速度成比例改变相位的原理。由于它能够实现精确的血流动力学特征描述,该技术对于评估主动脉缩窄的严重程度特别有用。通过对侧支循环的存在和方向进行定性评估,速度编码电影MR成像可提供有关梗阻的存在和严重程度的信息。它还允许对关键血流动力学参数进行准确量化,如流速、流量以及跨缩窄部位的压力梯度——这些功能信息对于术前规划和介入后监测均具有临床实用性。近期经验结果表明,速度编码电影MR成像也可能适用于检测支架置入或血管成形术后的再狭窄。

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