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[甲型病毒性肝炎和戊型病毒性肝炎的流行病学鉴别诊断体征]

[The epidemiological differential diagnostic signs of viral hepatitis A and viral hepatitis E].

作者信息

Beliakov V D, Khozhimirzaev A Kh, Ovezov A O

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1991 Aug(8):36-40.

PMID:1835233
Abstract

A retrospective epidemiologic analysis of cases diagnosed as hepatitis A (HA) has been made in territories characterized by high intensity (4 towns in Central Asia) and low intensity (Novomoskovsk, Tula Province) of the epidemic process development. Morbidity structures for different age and social groups of the population, as well as the morbidity time course, both annual and over many years, were analyzed over 1973-1986. Specific features in the development of the epidemic process in HA and hepatitis E (HE), formerly called hepatitis non-A, non-B with the fecal/oral mechanism of the infection transmission, were studied. Twelve epidemiological differential diagnostic signs of these two infections were formulated, classified, and validated. Contribution of centralized water supply and sewage systems to the development of HE epidemic process and the regulating role of infectious immunological mechanisms in the development of HA epidemic process were demonstrated.

摘要

对在流行过程发展强度高(中亚4个城镇)和强度低(图拉省新莫斯科夫斯克)地区诊断为甲型肝炎(HA)的病例进行了回顾性流行病学分析。分析了1973 - 1986年期间不同年龄和社会群体的发病率结构,以及年度和多年的发病时间进程。研究了甲型肝炎(HA)和戊型肝炎(HE,以前称为非甲非乙型肝炎)以粪 - 口传播机制传播时流行过程发展的具体特征。制定、分类并验证了这两种感染的12种流行病学鉴别诊断指标。证明了集中供水和污水系统对戊型肝炎流行过程发展的作用,以及感染免疫机制在甲型肝炎流行过程发展中的调节作用。

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