Lynde C B, Kraft J N, Lynde C W
Faculty of Medicine, University of Toronto, Toronto, ON, Canada.
Skin Therapy Lett. 2008 Feb;13(1):6-9.
There exists a multitude of medical conditions that cause intractable itch, or pruritus. The successful management of this symptom depends explicitly on establishing the underlying cause. Studies have shown that drugs not traditionally used in the treatment of cutaneous disorders, such as opiate receptor antagonists, antidepressants, and antiepileptics, can provide symptomatic relief of intractable itch. These novel antipruritic agents will be explored in this review.
存在多种导致顽固性瘙痒（即瘙痒症）的医学病症。成功管理这一症状明确取决于确定潜在病因。研究表明，传统上不用于治疗皮肤疾病的药物，如阿片受体拮抗剂、抗抑郁药和抗癫痫药，可缓解顽固性瘙痒的症状。本综述将探讨这些新型止痒药。
